The Arg282Ser missense mutation in APOA5 gene determines a reduction of triglyceride and LDL-cholesterol in children, together with low serum levels of apolipoprotein A-V

Table 3 Multiple linear regression analysis

Independent Variable	Standardized Regression Coefficients	t value	P
Age	0.015	0.311	0.756
BMI	−0.022	−0.522	0.602
Gender	0.045	1.337	0.182
TANNER’S STAGE	−0.125	−2.754	0.006
Arg282Ser SNP	−0.091	−2.743	0.006
HOMA-IR	0.058	1.597	0.111

Total cholesterol is the dependent variable
Abbreviations: BMI body mass index, HOMA-IR homeostatic model assessment of insulin resistance
P values <0.05 are considered significant

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