The Arg282Ser missense mutation in APOA5 gene determines a reduction of triglyceride and LDL-cholesterol in children, together with low serum levels of apolipoprotein A-V

Table 4 Multiple linear regression analysis

Independent Variable	Standardized Regression Coefficients	t value	P
Age	0.007	0.133	0.894
BMI	−0.44	−1.039	0.299
Gender	0.025	0.738	0.460
TANNER’S STAGE	−0.090	−1.966	0.050
Arg282Ser SNP	−0.076	−2.294	0.022
HOMA-IR	0.102	2.809	0.005

LDL- cholesterol is the dependent variable
Abbreviations: BMI body mass index, HOMA-IR homeostatic model assessment of insulin resistance
P values <0.05 are considered significant

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