Group | 0 weeks | 4 weeks | 7 weeks | |
---|---|---|---|---|
Body weight (kg) | ND | 3.5 ± 0.2 | 3.7 ± 0.2a | 3.9 ± 0.2a,b |
CD | 3.6 ± 0.2 | 3.8 ± 0.2a | 3.9 ± 0.1a | |
CD + Col | 3.5 ± 0.1 | 3.7 ± 0.2a | 3.8 ± 0.1a,b | |
Glu (mg/dL) | ND | 165.00 ± 36.17 | 136.00 ± 25.62 | 164.17 ± 17.18 |
CD | 159.86 ± 15.76 | 195.00 ± 41.05c,e | 198.29 ± 27.53e | |
CD + Col | 170.20 ± 26.54 | 143.50 ± 25.78 | 157.10 ± 30.98 | |
TC (mg/dL) | ND | 56.33 ± 12.14 | 40.33 ± 13.06 | 35.83 ± 8.42 |
CD | 51.86 ± 12.25 | 404.43 ± 36.97a,c | 449.86 ± 8.78a,b,c | |
CD + Col | 54.70 ± 18.01 | 430.90 ± 25.74a,c | 453.90 ± 12.33a,b,c | |
HDL-C (mg/dL) | ND | 17.67 ± 1.63 | 28.17 ± 7.57 | 27.33 ± 6.74 |
CD | 16.14 ± 2.67 | 81.71 ± 18.54a,c | 117.14 ± 22.34a,b,c | |
CD + Col | 16.50 ± 4.48 | 127.00 ± 28.78a,c,d | 109.10 ± 37.10a,b,c | |
LDL-C (mg/dL) | ND | 19.52 ± 6.62 | 3.33 ± 6.62a,d,e | 2.33 ± 2.42a |
CD | 17.28 ± 6.51 | 315.57 ± 23.64a,c | 306.57 ± 28.86a,c | |
CD + Col | 19.89 ± 12.42 | 294.78 ± 26.71a,c | 334.50 ± 35.26a,b,c | |
TG (mg/dL) | ND | 99.83 ± 42.68 | 47.00 ± 13.86a | 31.17 ± 4.40a,b,d |
CD | 91.00 ± 35.75 | 34.14 ± 15.54a | 130.00 ± 133.18b | |
CD + Col | 90.20 ± 31.31 | 42.80 ± 17.40a | 50.60 ± 32.19a,b | |
SGOT/AST (U/L) | ND | 20.42 ± 5.42 | 30.67 ± 6.83a | 29.83 ± 4.02a |
CD | 19.92 ± 6.08 | 39.14 ± 9.67a,e | 22.50 ± 4.04b,c,e | |
CD + Col | 21.69 ± 7.48 | 25.80 ± 8.61 | 41.70 ± 20.71 | |
SGPT/ALT (U/L) | ND | 28.81 ± 9.57 | 49.17 ± 11.55a | 41.33 ± 10.80a |
CD | 33.14 ± 10.10 | 41.86 ± 10.54 | 30.00 ± 13.51 | |
CD + Col | 35.35 ± 11.84 | 47.70 ± 16.20 | 56.70 ± 29.93 | |
γGT (U/L) | ND | 9.19 ± 1.97 | 13.17 ± 3.19 | 11.17 ± 1.86 |
CD | 9.56 ± 0.93 | 11.29 ± 2.69 | 20.00 ± 23.93 | |
CD + Col | 9.65 ± 1.29 | 11.70 ± 2.83a | 9.30 ± 2.21a,b | |
ALP (U/L) | ND | 66.67 ± 23.31 | 105.23 ± 31.63 | 78.77 ± 20.85 |
CD | 69.00 ± 6.83 | 95.40 ± 27.07 | 54.73 ± 40.37 | |
CD + Col | 73.10 ± 14.77 | 107.87 ± 11.75a | 52.67 ± 18.29a,b | |
Creatinine (mg/dL) | ND | 1.08 ± 0.6 | 1.18 ± 0.07 | 1.07 ± 0.08 |
CD | 1.12 ± 0.16 | 1.24 ± 0.10 | 1.18 ± 0.13 | |
CD + Col | 1.08 ± 0.17 | 1.05 ± 0.14c,d | 1.13 ± 0.08 | |
Total protein (g/dL) | ND | 5.75 ± 0.24 | 6.20 ± 0.38 | 5.82 ± 0.29 |
CD | 5.88 ± 0.23 | 6.47 ± 0.26 | 6.28 ± 0.86 | |
CD + Col | 5.73 ± 0.34 | 6.09 ± 0.47 | 5.96 ± 0.26 |