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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: 17β-estradiol lowers triglycerides in adipocytes via estrogen receptor α and it may be attenuated by inflammation

Fig. 2

17β-E2 lowers triglyceride content in differentiated 3T3-L1 cells possibly via ERα. Differentiated 3T3-L1 adipocytes were starved in serum free DMEM for 12 h and then were treated with 0.1% DMSO alone, 1 μM 17β-E2, 10 μM MPP (pre-treated for 1 h) plus 1 μM 17β-E2 or 10 μM PHTPP (pre-treated for 1 h) plus 1 μM 17β-E2 for 48 h. Intracellular TG contents were normalized by total protein. The data were presented as the mean ± SD, n = 3 for each group. *P < 0.05, compared with Control group; #P < 0.05, compared with 17β -E2 group. MPP: a selective estrogen receptor α inhibitor, PHTPP: a selective estrogen receptor β inhibitor

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Lipids in Health and Disease

ISSN: 1476-511X