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Table 4 Risk of ESRD and all-cause mortality with each 0.1 mmol/L increase of HDL-C levels by eGFR

From: Effect of low and high HDL-C levels on the prognosis of lupus nephritis patients: a prospective cohort study

 

eGFR ≥60 ml/min/1.73m2 (n = 518)

eGFR < 60 ml/min/1.73m2 (n = 257)

eGFR category * HDL-C Interaction

HR (95% CI)

P a

HR (95% CI)

P a

β

P b

ESRD

0.92 (0.83, 1.04)

0.173

1.11 (1.01, 1.23)

0.036

−1.738

0.005

All-cause mortality

0.86 (0.75, 0.98)

0.021

0.96 (0.87, 1.06)

0.429

−1.156

0.091

  1. Note: aAdjusted for age, gender, weight, smoking status, eGFR, SLEDAI, 24-h proteinuria, total cholesterol, triglyceride, LDL-C, diabetes mellitus, hypertension, hypoalbuminemia, disease duration, lipid-lowering therapy and immunosuppressive treatment. bAdjusted for age, gender, weight, smoking status, SLEDAI, 24-h proteinuria, total cholesterol, triglyceride, LDL-C, diabetes mellitus, hypertension, hypoalbuminemia, disease duration, lipid-lowering therapy and immunosuppressive treatment. *Interactions between eGFR category and HDL-C levels
  2. HR hazard ratio; 95% CI 95% confidence interval
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Lipids in Health and Disease

ISSN: 1476-511X