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Table 3 Brain fatty acid composition

From: Comparative analyses of DHA-Phosphatidylcholine and recombination of DHA-Triglyceride with Egg-Phosphatidylcholine or Glycerylphosphorylcholine on DHA repletion in n-3 deficient mice

Fatty acid (%) 0 day after weaning 4 days after weaning 7 days after weaning 14 days after weaning
n-3 Adq n-3 Def n-3 Adq n-3 Def DHA-PC DHA-TG + PC DHA-TG + α-GPC n-3 Adq n-3 Def DHA-PC DHA-TG + PC DHA-TG + α-GPC n-3 Adq n-3 Def DHA-PC DHA-TG + PC DHA-TG + α-GPC
14:0 0.55 ± .0.04 0.61 ± 0.04 0.63 ± 0.03 0.65 ± 0.04 0.69 ± 0.03 0.60 ± 0.04 0.61 ± 0.03 0.49 ± 0.01 0.44 ± 0.06 0.45 ± 0.03 0.52 ± 0.03 0.56 ± 0.03 0.70 ± 0.03 0.76 ± 0.02 0.66 ± 0.03 0.66 ± 0.04 0.74 ± 0.05
16:0 22.26 ± 0.27 22.54 ± 0.16 21.23 ± 0.40 21.52 ± 0.30 21.07 ± 0.25 21.48 ± 0.18 21.86 ± 0.17 21.17 ± 0.28 21.09 ± 0.21 20.89 ± 0.17 21.13 ± 0.31 21.54 ± 0.15 20.28 ± 0.31 20.34 ± 0.27 20.41 ± 0.21 20.55 ± 0.23 20.73 ± 0.31
18:0 20.53 ± 0.22 19.95 ± 0.23 19.51 ± 0.31 19.32 ± 0.29 20.06 ± 0.25 19.42 ± 0.25 19.59 ± 0.19 19.38 ± 0.18 19.51 ± 0.21 19.64 ± 0.27 19.84 ± 0.20 19.88 ± 0.23 19.17 ± 0.25 19.35 ± 0.31 19.37 ± 0.22 19.72 ± 0.23 19.61 ± 0.28
SFAs 47.84 ± 0.46 47.42 ± 0.36 47.63 ± 0.36 47.48 ± 0.47 48.14 ± 0.40 47.57 ± 0.54 47.35 ± 0.36 46.55 ± 0.44 46.34 ± 0.33 46.69 ± 0.25 46.13 ± 0.27 45.84 ± 0.39 45.79 ± 0.36 45.92 ± 0.44 45.65 ± 0.25 46.69 ± 0.27 45.69 ± 0.25
16:1n-7 1.32 ± 0.09 1.01 ± 0.12 1.35 ± 0.08 1.21 ± 0.08 1.37 ± 0.09 1.26 ± 0.07 1.37 ± 0.06 1.27 ± 0.03 1.24 ± 0.05 1.44 ± 0.04 1.29 ± 0.10 1.26 ± 0.08 1.38 ± 0.07 1.27 ± 0.05 1.34 ± 0.02 1.34 ± 0.05 1.27 ± 0.01
18:1n-9 14.34 ± 0.24 13.04 ± 0.33 14.96 ± 0.39 14.76 ± 0.27 15.36 ± 0.20 14.75 ± 0.25 14.89 ± 0.23 15.16 ± 0.19 14.98 ± 0.19 15.57 ± 0.28 15.01 ± 0.18 15.08 ± 0.13 15.32 ± 0.32 15.48 ± 0.17 15.96 ± 0.26 15.97 ± 0.18 15.41 ± 0.31
18:1n-7 2.78 ± 0.18 2.89 ± 0.14 2.68 ± 0.15 2.74 ± 0.13 2.69 ± 0.14 2.61 ± 0.11 2.53 ± 0.09 2.55 ± 0.19 2.49 ± 0.16 2.41 ± 0.14 2.82 ± 0.10 2.44 ± 0.14 2.57 ± 0.17 2.35 ± 0.06 2.49 ± 0.11 2.68 ± 0.06 2.53 ± 0.08
MUFAs 22.20 ± 0.47 20.76 ± 0.48 21.86 ± 0.29 21.55 ± 0.33 22.31 ± 0.23 22.51 ± 0.18 22.59 ± 0.22 22.54 ± 0.33 22.86 ± 0.31 22.43 ± 0.27 22.50 ± 0.20 22.58 ± 0.30 22.76 ± 0.30 23.37 ± 0.39 23.07 ± 0.19 23.78 ± 0.27 23.39 ± 0.31
18:2n-6 0.35 ± 0.02 0.46 ± 0.03* 0.42 ± 0.03a 0.54 ± 0.03b 0.61 ± 0.02c 0.58 ± 0.01bc 0.53 ± 0.02b 0.49 ± 0.03 0.52 ± 0.02 0.56 ± 0.03 0.54 ± 0.02 0.51 ± 0.02 0.57 ± 0.02 0.89 ± 0.03 0.42 ± 0.03 0.46 ± 0.02 0.39 ± 0.02
20:4n-6 10.19 ± 0.20 11.97 ± 0.27** 10.20 ± 0.16a 11.72 ± 0.17b 10.34 ± 0.18a 10.17 ± 0.16a 10.14 ± 0.14a 10.04 ± 0.21a 11.70 ± 0.25b 10.01 ± 0.14a 9.96 ± 0.27a 9.97 ± 0.11a 10.35 ± 0.09c 11.45 ± 0.09d 9.32 ± 0.10b 9.17 ± 0.11b 8.81 ± 0.10a
22:4n-6 2.13 ± 0.16 3.32 ± 0.25** 2.22 ± 0.08a 3.12 ± 0.05c 2.80 ± 0.11b 22.92 ± 0.07bc 3.02 ± 0.06bc 2.30 ± 0.11a 3.05 ± 0.12b 2.53 ± 0.24a 2.58 ± 0.07a 2.42 ± 0.09a 2.02 ± 0.08b 3.13 ± 0.07c 1.79 ± 0.06ab 1.86 ± 0.08ab 1.73 ± 0.08a
22:5n-6 1.40 ± 0.15 7.20 ± 0.19** 1.30 ± 0.07a 7.01 ± 0.12d 4.84 ± 0.09b 5.55 ± 0.11c 5.30 ± 0.07c 1.21 ± 0.12a 6.57 ± 0.19c 4.19 ± 0.17b 4.39 ± 0.18b 4.44 ± 0.14b 1.19 ± 0.07a 6.31 ± 0.12c 2.44 ± 0.11b 2.38 ± 0.13b 2.69 ± 0.09b
N-6 15.37 ± 0.25 23.75 ± 0.27** 15.04 ± 0.15a 23.31 ± 0.19c 19.58 ± 0.24b 20.01 ± 0.35b 19.74 ± 0.17b 14.79 ± 0.33a 22.89 ± 0.18d 18.01 ± 0.31b 18.97 ± 0.32bc 18.31 ± 0.21ab 14.63 ± 0.46a 22.77 ± 0.69b 14.05 ± 0.39a 14.31 ± 0.43a 14.17 ± 0.26a
22:6n-3 14.30 ± 0.15 7.50 ± 0.16** 15.01 ± 0.17c 7.60 ± 0.15a 9.31 ± 0.19b 9.50 ± 0.15b 9.82 ± 0.24b 15.54 ± 0.25d 7.79 ± 0.18a 12.21 ± 0.21bc 11.90 ± 0.19b 12.70 ± 0.20c 16.20 ± 0.15c 8.10 ± 0.09a 16.51 ± 0.09c 14.72 ± 0.12b 16.12 ± 0.14c
N-3 14.50 ± 0.23 8.07 ± 0.19** 15.49 ± 0.19c 7.75 ± 0.16a 9.97 ± 0.18b 9.91 ± 0.19b 10.32 ± 0.18b 16.12 ± 0.23d 7.91 ± 0.22a 12.87 ± 0.12bc 12.40 ± 0.23b 13.27 ± 0.15c 16.82 ± 0.15c 8.26 ± 0.12a 17.23 ± 0.13c 15.22 ± 0.14b 16.75 ± 0.19c
PUFAs 29.96 ± 0.63 31.82 ± 0.65 30.51 ± 0.43 31.06 ± 0.51 29.55 ± 0.73 29.92 ± 0.50 30.06 ± 0.39 30.91 ± 0.56 30.80 ± 0.39 30.88 ± 0.43 31.37 ± 0.55 31.58 ± 0.36 31.45 ± 0.47 31.03 ± 0.77 31.28 ± 0.38 29.53 ± 0.45 30.92 ± 0.36
N-6/ N-3 1.06 ± 0.02 2.94 ± 0.04** 0.97 ± 0.01a 3.02 ± 0.07c 1.96 ± 0.04b 2.01 ± 0.03b 1.91 ± 0.04b 0.92 ± 0.01a 2.89 ± 0.07d 1.40 ± 0.01b 1.53 ± 0.01c 1.38 ± 0.01b 0.87 ± 0.03b 2.76 ± 0.07a 0.82 ± 0.03b 0.94 ± 0.03b 0.85 ± 0.02b
Total 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100 100 100 100 100 100 100 100 100 100
  1. Only major Fatty acid methyl esters were presented; thus they do not add up to 100%. EPA (20:5n-3) were not detected (<0.01%, trace). Each parameter was presented as the mean ± SEM (n = 6). * p < 0.05, ** p < 0.01, significant difference compared to the n-3 Adq group at 3 weeks of age determined by Student’s t-test. Different letters indicate significant difference at p < 0.05 among all dietary groups after 3 weeks of age
  2. SFA saturated fatty acid, MUFA monounsaturated fatty acid, PUFA polyunsaturated fatty acid, N-6 n-6 polyunsaturated fatty acids, N-3 n-3 polyunsaturated fatty acids
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Lipids in Health and Disease

ISSN: 1476-511X