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Table 3 Distributions of alleles and genotypes between T2DM patients and control subjects in males

From: Association of polymorphisms in LEPR with type 2 diabetes and related metabolic traits in a Chinese population

Polymorphism T2DM Non-diabetic Unadjusted Pa Adjusted OR(95% CI)/Pb
rs3806318 n = 363 n = 393   
 AA 287(79.1%) 302(76.9%) 0.756 1
 AG 73(20.1%) 87(22.1%)   1.020(0.439–2.370)/0.964
 GG 3(0.8%) 4(1.0%)   0.880(0.404–1.915)/0.747
 A 647(89.1%) 691(87.9%) 0.463 1
 G 79(10.9%) 95(12.1%)   0.894(0.639–1.251)/0.514
rs1327118 n = 361 n = 390   
 CC 293(81.2%) 300(76.9%) 0.252 1
 CG 65(18.0%) 83(21.3%)   1.491(0.628–3.541)/0.365
 GG 3(0.8%) 7(1.8%)   0.512(0.230–1.136)/0.100
 C 651(90.2%) 683(87.6%) 0.110 1
 G 71(9.8%) 97(12.4%)   0.707(0.504–0.991)/0.044
  1. T2DM type 2 diabetes mellitus
  2. aP-values were obtained by chi-square tests
  3. bP-values were obtained by logistic regression analysis adjusted for age, BMI
  4. P values in boldface are significant