Protective effects of Mentha piperita L. leaf essential oil against CCl4 induced hepatic oxidative damage and renal failure in rats

Table 4 Effects of CCl₄,MpEO and their combination MpEO/CCl₄ on lipid profile in serum of control and experimental rats

Treatment and parameters	T-Cholesterol (mmol/l)	T-Triglycerides (mmol/l)	HDL (mmol/L)	LDL (mmol/l)
Control	1.133 ± 0.033	0.736 ± 0.075	1.413 ± 0.023	0.123 ± 0.014
CCl₄	1.750 ± 0.028^***	1.743 ± 0.078^***	0.446 ± 0.074^***	0.726 ± 0.053^***
SL/CCl₄	0.966 ± 0.033^###	1.043 ± 0.012^###	1.240 ± 0.030^###	0.176 ± 0.008^###
MpEO^a/CCl₄	1.606 ± 0.063	1.610 ± 0.041	0.690 ± 0.135	0.640 ± 0.066
MpEO^b/CCl₄	1.376 ± 0.076^##	1.196 ± 0.039^##	0.873 ± 0.053^##	0.253 ± 0.024^##
MpEO^c/CCl₄	1.033 ± 0.033^###	1.050 ± 0.010^###	1.296 ± 0.039^###	0.186 ± 0.017^###
MpEO^c	1.100 ± 0.115	0.763 ± 0.069	1.210 ± 0.106	0.113 ± 0.006

TC Total cholesterol (mmol/l), HDL high density lipoprotein (mmol/l), TG triglyceride (mmol/l) and LDL low density lipoprotein (mmol/l). ^aMpEO (5 mg/kg BW), ^bMpEO (15 mg/kg BW), ^cMpEO (40 mg/kg BW), SL: Silymarin (50 mg/kg BW)
Values are mean ± SEM for eight rats in each group. CCl4, MpEO and MpEO/CCl₄ treated groups vs control group; ** p < 0.01, *** p < 0.001, CCl₄ group vs MpEO/CCl₄ group; ^# p < 0.05, ^{# #} p < 0.01, ^{# # #} p < 0.001

ISSN: 1476-511X