Skip to main content

Table 2 Genotypic and allelic frequencies of the DOCK7-ANGPTL3 SNPs in controls and cases

From: DOCK7-ANGPTL3 SNPs and their haplotypes with serum lipid levels and the risk of coronary artery disease and ischemic stroke

SNP/Genotype/Allele

Control (%)

CAD (%)

IS (%)

P CAD

P IS

Rs1748195

 CC

361 (58.1)

303 (53.3)

311 (57.7)

  

 CG

227 (36.6)

216 (38.0)

188 (34.9)

  

 GG

33 (5.3)

49 (8.7)

40 (7.4)

0.047

0.321

 C

949 (76.4)

822 (72.4)

810 (75.1)

  

 G

293 (23.6)

314 (27.6)

268 (24.9)

0.024

0.476

 PHWE

0.728

0.240

0.123

  

 CC/CG

588 (94.7)

519 (91.3)

499 (92.6)

  

 GG

33 (5.3)

49 (8.7)

40 (7.4)

0.024

0.140

Rs12563308

 TT

534 (86.0)

517 (91.0)

479 (88.8)

  

 CT

84 (13.5)

48 (8.5)

57 (10.6)

  

 CC

3 (0.5)

3 (0.5)

3 (0.6)

0.021

0.305

 T

1152 (92.8)

1082 (95.2)

1015 (94.2)

  

 C

80 (7.2)

54 (4.8)

63 (5.8)

0.067

0.518

 PHWE

0.876

0.112

0.364

  

 TT

534 (86.0)

517 (91.0)

479 (88.8)

  

 CT/CC

87 (14.0)

51 (9.0)

60 (11.2)

0.007

0.142

  1. SNP single nucleotide polymorphisms, CAD coronary artery disease, IS ischemic disease, HWE Hardy- Weinberg equilibrium, PHWE the P value of the Hardy-Weinberg equilibrium, PCAD the P value between CAD patients and controls, PIS the P value between IS patients and controls