Fig. 6From: Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivoIsolated pancreatic islet function was evaluated after treatment with STZ injection, high-fat diet, and STZ injection combined with high-fat diet in rats. a mRNA levels of amylin. b mRNA levels of insulin. c Representative images of WB for IRβ expression. Relative quantitation of IRβ expression was performed and shown in (d). e Representative images of WB for cleaved caspase-3 expression. f Relative quantitation of cleaved caspase-3 expression was performed. * denotes p < 0.05 compared with the control group; ** denotes p < 0.01 compared with the control group. n = 4. Two-way ANOVA was used with post hoc testBack to article page