Plasma angiopoietin-like 4 is related to phospholipid transfer protein activity in diabetic and non-diabetic subjects: role of enhanced low grade inflammation

Table 3 Multivariable regression analyses showing independent relationships of angiopoietin-like 4 (ANGPTL4) levels and phospholipid transfer protein (PLTP) activity with high sensitivity C-reactive protein (hsCRP), glycemia and plasma lipids in 77 subjects (41 subjects with and 36 subjects without Type 2 diabetes mellitus)

	Model A 1 ANGPTL4		Model A 2 ANGPTL4		Model B 1 PLTP activity		Model B 2 PLTP activity
	β	p-value	β	p-value	β	p-value	β	p-value
Age	0.173	0.12	0.209	0.065	0.094	0.43	0.119	0.33
Sex (men vs. women)	0.226	0.043	0.263	0.014	−0.135	0.25	−0.057	0.62
T2DM	0.088	0.48			0.376	0.006
Glucose			−0.081	0.51			0.276	0.034
hsCRP	0.327	0.002	0.315	0.003	0.229	0.037	0.299	0.034
NEFA	0.360	0.002	0.374	0.001	0.020	0.87	0.105	0.37
Total cholesterol	−0.284	0.009	−0.308	0.005	0.014	0.90	0.025	0.83
Triglycerides	0.081	0.47		0.105	0.39	0.10	0.166	0.21

Models A: ANGPTL4 as dependent variable
Models B: PLTP activity as dependent variable
Models 1: including Type 2 diabetes mellitus (T2DM) as independent variable
Models 2: including fasting glucose as independent variable
β: standardized regression coefficient, NEFA non-esterified fatty acids, T2DM Type 2 diabetes mellitus. ANGPTL4, hsCRP and triglycerides are log_e transformed

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