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Table 4 Association of the SNPs with lipid traits individually

From: GWAS implicated risk variants in different genes contribute additively to increase the risk of coronary artery disease (CAD) in the Pakistani subjects

SNP Genotype LDL-C HDL-C TC TG
rs10757274 AA 99.6 ± 28.2 53.4 ± 19 196.7 ± 52.3 205.4 ± 68.9
AG 97.3 ± 27 53.9 ± 17.4 195.2 ± 51.8 203.2 ± 71
GG 99.6 ± 27.1 50.8 ± 14.6 197.6 ± 54 203.4 ± 68.2
β(Se) 0.06 (1.52) 1.27 (0.96) 0.5 (2.9) 1.01 (3.9)
p-value 0.97 0.188 0.88 0.794
rs17465637 AA 96.3 ± 23 54.8 ± 18.1 190.7 ± 52.3 196.5 ± 68.8
AC 99.4 ± 26.8 53.6 ± 16.4 196.9 ± 52.0 206.6 ± 68.2
CC 98 ± 29.1 51.8 ± 17.9 197.1 ± 53 217.0 ± 76
β (se) 0.17 (1.6) 1.6 (1.0) 2.3 (3.1) 10.2 (4.1)
p-value 0.92 0.13 0.46 0.01
rs7025486 GG 98.3 ± 26.5 53.7 ± 17.0 195.4 ± 50.7 203 ± 70.7
AG 99.0 ± 28.0 52.9 ± 17.7 197.9 ± 54.1 206.7 ± 70.4
AA 96.8 ± 28.5 50.0 ± 16.0 192.5 ± 53.4 194.4 ± 61
β (Se) 0.19 (1.7) 1.5 (1.0) 0.07 (3.2) 1.3 (4.3)
p-value 0.91 0.16 0.98 0.76
rs17228212 TT 98.3 ± 25.5 53.1 ± 17.2 195.4 ± 52.8 204.5 ± 68.4
CT 99.2 ± 30.2 52.7 ± 17.8 198.3 ± 52.2 203.3 ± 71
CC 95.8 ± 33.3 53.1 ± 14.6 192.5 ± 50 195.6 ± 81
β (Se) 0.07 (2) 0.3 (1.2) 1.2 (3.7) 2.5 (5)
p-value 0.97 0.83 0.76 0.62
rs9818870 CC 97.7 ± 26.6 53.3 ± 17 196.8 ± 53.8 203.2 ± 68
CT 102.4 ± 29.6 52 ± 18.2 192.4 ± 43.7 203.3 ± 76.5
TT 102.9 ± 41.8 48.3 ± 17.7 206.6 ± 63.8 252.5 ± 74.0
β (Se) 4.1 (2.6) 1.6 (1.6) 1.9 (5) 6.7 (6.7)
p-value 0.11 0.35 0.7 0.32
rs1746048 TT 97.1 ± 28.2 53.5 ± 19.2 185.8 ± 50.3 205.1 ± 61.2
CT 100.4 ± 26.6 52.6 ± 16.9 195.1 ± 51 205.9 ± 72.9
CC 96.9 ± 27.8 53.3 ± 17.1 200.1 ± 54.1 201.3 ± 68.6
β (Se) 1.2 (1.6) 0.1 (1) 6.5 (3.1) 2.7 (4.2)
p-value 0.47 0.9 0.04 0.51
  1. β (Se) is the effect size with standard error. Values are mentioned as mean ± SD. The analyses were adjusted for age and gender