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Table 5 Comparison of Mean lipid parameter values across GRS quartiles

From: GWAS implicated risk variants in different genes contribute additively to increase the risk of coronary artery disease (CAD) in the Pakistani subjects

Parameter Q1 Q2 Q3 β-effect p-value
TC (mg/dL) 192.6 ± 4.3 197.2 ± 2.4 196.6 ± 3.3 0.049 0.676
TG (mg/dL) 160.2 ± 6.1 202.4 ± 3.2 212.4 ± 6.1 0.064 0.022
HDL-C (mg/dL) 53.8 ± 1.5 53.1 ± 1.8 48.3 ± 3.1 −0.064 0.536
LDL-C (mg/dL) 93.9 ± 2.7 93.6 ± 1.5 104.8 ± 1.3 0.020 0.449
  1. Q1: GRS 0–4, Q2: GRS 5–8, Q3: GRS 9–12