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Table 2 Effect of myrtle berries seeds aqueous extract (MBSAE) on chronic EtOH-induced haematological parameters changes

From: Myrtle berries seeds aqueous extract abrogates chronic alcohol consumption-induced erythrocytes osmotic stability disturbance, haematological and biochemical toxicity

Parameters

Experimental groups

Control

EtOH

EtOH + MBSAE-25

EtOH + MBSAE-50

EtOH + MBSAE-100

RBC count (106/μl)

7.88 ± 0.76

6.47 ± 0.28

7.33 ± 0.41

7.47 ± 0.38

7.55 ± 0.77

Hb (g/dl)

14.63 ± 0.44

9.22 ± 0.21*

12.56 ± 0.32#

13.70 ± 0.88#

14.04 ± 0.90#

Ht (%)

47.58 ± 1.71

39.66 ± 1.44*

41.72 ± 1.14

43.58 ± 1.77#

45.36 ± 2.16#

MCV (mm3/RBC)

53.61 ± 2.43

68. 33 ± 2.71*

61.44 ± 3. 07

58. 33 ± 2.81#

55. 44 ± 2.09#

MCH (pg/RBC)

21.73 ± 1.51

19.39 ± 1.66

20.19 ± 2.39

20.08 ± 2.80

21.09 ± 2.26

MCHC (g/dl)

35.09 ± 1.12

30.22 ± 1.66*

32.14 ± 1.85

34.12 ± 2. 63#

34.80 ± 2. 47#

Plt (103/μl)

741.70 ± 73.82

222.31 ± 72.88*

620.91 ± 66. 66#

681.15 ± 68.32#

711.06 ± 77.12#

WBC (103/μl)

10.31 ± 0.45

17.21 ± 2.33*

13.51 ± 0.89#

12.77 ± 1.08#

10.81 ± 0.74#

  1. Animals were daily treated with various doses of the MBSAE (25, 50 and 100 mg kg− 1, b.w., p.o.) or vehicle (NaCl 0.9%) before ethanol (30%, v/v, 10 mL kg− 1, b.w.) intoxication during two months. The data are expressed as mean ± S.E.M. (n = 10), *: p < 0.05 compared to control group and #: p < 0.05 compared to EtOH group
  2. RBC Red blood cell, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, Hb Hemoglobin, Ht Hematocrit, MCHC mean corpuscular hemoglobin concentration, Plt Platelet and WBC white blood cells
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Lipids in Health and Disease

ISSN: 1476-511X