Variables
|
Number of SMD included
|
Subgroups
|
Pooled OR (random effect)
|
95% CI
|
I2 (%)
|
Overall I2 (%)
|
---|
Triglycerides
|
Type of disease
|
5
|
PCOS
|
−0.74
|
−1.66, 0.18
|
91.7
|
93.2
|
7
|
Non-PCOS
|
−1.58
|
−2.32, −0.85
|
92.1
|
Dosage of inositol (mg/day)
|
6
|
≥2000
|
−0.83
|
−1.49, − 0.18
|
83.4
|
6
|
<2000
|
−1.69
|
−2.69, −0.68
|
96.2
|
Duration of study (week)
|
5
|
≥14
|
−1.64
|
−2.94, −0.34
|
93.4
|
7
|
<14
|
−0.99
|
−1.67, − 0.32
|
93.1
|
Type of intervention
|
4
|
DCI
|
−0.32
|
−0.66, 0.01
|
0.0
|
6
|
MI
|
−1.15
|
−1.91, −0.39
|
94.0
|
2
|
MI + DCI
|
−3.37
|
−6.00, −0.75
|
94.2
|
Total cholesterol
|
Type of disease
|
5
|
PCOS
|
−0.86
|
−1.72, − 0.02
|
90.3
|
93.6
|
6
|
Non-PCOS
|
−1.49
|
−2.51, −0.46
|
95.5
|
Dosage of inositol (mg/day)
|
5
|
≥2000
|
−0.82
|
−1.91, 0.28
|
92.2
|
6
|
<2000
|
−1.51
|
−2.38, −0.63
|
95.2
|
Duration of study (week)
|
5
|
≥14
|
−1.77
|
−3.31, −0.22
|
95.0
|
6
|
<14
|
−0.74
|
−1.33, − 0.15
|
90.5
|
Type of intervention
|
4
|
DCI
|
−0.22
|
−0.62, 0.18
|
26.2
|
5
|
MI
|
−0.91
|
−1.59, − 0.24
|
91.9
|
2
|
MI + DCI
|
−3.76
|
−5.68, −1.85
|
88.2
|
LDL-cholesterol
|
Type of disease
|
3
|
PCOS
|
−0.60
|
−1.51, 0.31
|
86.1
|
92.2
|
2
|
Non-PCOS
|
−1.84
|
−3.41, 0.26
|
93.1
|
Dosage of inositol (mg/day)
|
3
|
≥2000
|
−0.86
|
−2.27, 0.54
|
93.2
|
2
|
<2000
|
−2.00
|
−3.98, −0.03
|
94.8
|
Duration of study (week)
|
4
|
≥14
|
−1.39
|
−2.78, −0.01
|
94.0
|
1
|
<14
|
−1.03
|
− 1.37, −0.70
|
0.0
|
Type of intervention
|
2
|
DCI
|
−0.15
|
− 0.61, 0.30
|
0.0
|
1
|
MI
|
−1.03
|
−1.37, −0.70
|
–
|
2
|
MI + DCI
|
−2.59
|
−3.39, −1.81
|
56.7
|
HDL-cholesterol
|
Type of disease
|
3
|
PCOS
|
0.38
|
0.12, 0.64
|
2.4
|
89.4
|
7
|
Non-PCOS
|
0.14
|
−0.56, 0.84
|
92.7
|
Dosage of inositol (mg/day)
|
5
|
≥2000
|
0.01
|
−0.59, 0.62
|
81.1
|
5
|
<2000
|
0.37
|
−0.31, 1.04
|
92.2
|
Duration of study (week)
|
4
|
≥14
|
−0.61
|
−1.35, 0.14
|
83.5
|
6
|
<14
|
0.68
|
0.42, 0.95
|
55.1
|
Type of intervention
|
3
|
DCI
|
0.19
|
−0.17, 0.55
|
0.0
|
5
|
MI
|
0.72
|
0.42, 1.02
|
62.0
|
2
|
MI + DCI
|
−1.22
|
−1.73, −0.71
|
36.2
|
- MI myo-inositol, DCI D-chiro-Inositol, PCOS polycystic ovary syndrome