Fig. 10From: δ-Tocotrienol feeding modulates gene expression of EIF2, mTOR, protein ubiquitination through multiple-signaling pathways in chronic hepatitis C patientsEffect on tumor necrosis factor receptor1 (TNFR1) regulator of gene expression in plasma of total mRNAs obtained from δ-tocotrienol treatment of hepatitis C patients. The TNFR1 was down-regulated by δ-tocotrienol treatment, and belongs to a family of 20 in mammalian cells. TNF-α is an important cytokine involved in cell proliferation, differentiation, apoptosis, modulates immune responses and induction of inflammation. TNF-α functions through two receptors, TNFR1 and TNFR2. TNFR1 is expressed in human tissue, and TNFR2 is expressed in immune cellsBack to article page