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Table 12 Major signaling pathways affected by δ-tocotrienol treatment in chronic hepatitis C subjects

From: δ-Tocotrienol feeding modulates gene expression of EIF2, mTOR, protein ubiquitination through multiple-signaling pathways in chronic hepatitis C patients

Down-regulated by δ -tocotrienol treatment

Up-regulated by δ-tocotrienol treatment

Proliferation of immune cells

Cell death and survival

Proliferation of mononuclear leukocytes

Necrosis of malignant tumor

Viral infection

Gene expression

Free radical scavenging

Organismal Death

Endocrine system disorder, Diabetes mellitus

Cell death of cancer cells

Mobilization of Ca2+

Cell death of tumors

Replication of virus

 

HIV infection, replication of Influenza virus