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Table 12 Major signaling pathways affected by δ-tocotrienol treatment in chronic hepatitis C subjects

From: δ-Tocotrienol feeding modulates gene expression of EIF2, mTOR, protein ubiquitination through multiple-signaling pathways in chronic hepatitis C patients

Down-regulated by δ -tocotrienol treatment Up-regulated by δ-tocotrienol treatment
Proliferation of immune cells Cell death and survival
Proliferation of mononuclear leukocytes Necrosis of malignant tumor
Viral infection Gene expression
Free radical scavenging Organismal Death
Endocrine system disorder, Diabetes mellitus Cell death of cancer cells
Mobilization of Ca2+ Cell death of tumors
Replication of virus  
HIV infection, replication of Influenza virus