Fig. 1

Western diet and apoE gene deletion elevate blood lipids and aggravate atherosclerosis. a Total cholesterol (TC); (b) Triglycerides (TG); (c) High-density lipoprotein cholesterol (HDL-C) levels at 12 weeks in the plasma samples from four groups of mice; (d) Cross sections of aortic roots from four groups of mice were stained with Oil-Red-O; (e) Macrophage and smooth muscle cells staining of apoE KO mice; (f) En face Oil-Red-O staining of aortic specimens with the quantitive analysis on the right panel. Data are expressed as the mean ± SEM, n = 7~ 8 for each group. ^∗P < 005, ^∗∗∗P < 0001 versus wild type (WT) mice