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Table 1 Baseline Characteristics and Blood tests of the Study Participants

From: Plasma apolipoprotein E level is associated with the risk of endobronchial biopsy-induced bleeding in patients with lung cancer

Characteristics Biopsy-induced bleeding
No (n = 391) Yes (n = 224)
Age (y), median (range) 65.00 (32–85) 65.50 (36–82)
Sex, n (%)
 Female 94 (24.04) 41 (18.30)
 Man 297 (75.96) 183 (81.70)
Smoking, n (%)
 Never 158 (40.41) 68 (30.36)
 Former 56 (14.32) 44 (19.64)
 Current 177 (45.27) 112 (50.00)
SBP (mmHg) 132.34 ± 0.98 130.01 ± 1.37
DBP (mmHg) 77.95 ± 0.58 78.60 ± 0.82
Location of lesion, n (%)
 Peripheral bronchi 362 (92.58) 175 (78.12)
 Central airway 29 (7.42) 49 (21.88)
Stage, n (%)
 Early 237 (60.61) 98 (44.95)
 Advanced 154 (39.39) 120 (55.05)
Histological types, n (%)
 Adenocarcinoma 130 (33.25) 36 (16.07)
 Squamous cell carcinoma 175 (44.76) 134 (59.82)
 SCLC 67 (17.14) 41 (18.30)
 Others 19 (4.86) 13 (5.80)
COPD, n (%)
 No 365 (93.35) 208 (92.86)
 Yes 26 (6.65) 16 (7.14)
Hypertension, n (%)
 No 297 (75.96) 166 (74.11)
 Yes 94 (24.04) 58 (25.89)
Diabetes, n (%)
 No 370 (94.63) 214 (95.54)
 Yes 21 (5.37) 10 (4.46)
CHD, n (%)
 No 379 (96.93) 216 (96.43)
 Yes 12 (3.07) 8 (3.57)
Triglyceride (mmol/L) 1.24 ± 0.03 1.15 ± 0.05
TC (mmol/L) 4.19 ± 0.06 4.10 ± 0.06
HDLC (mmol/L) 1.18 ± 0.02 1.12 ± 0.02
LDLC (mmol/L) 2.84 ± 0.04 2.77 ± 0.05
Apo E (mg/dL) 3.90 ± 0.07 3.65 ± 0.10
Apo B (g/L) 1.02 ± 0.02 0.99 ± 0.02
Homocysteine (μmol/L) 15.05 ± 0.43 20.48 ± 5.23
WBC (× 109/L) 7.31 ± 0.16 7.62 ± 0.22
Neutrophils (×109/L) 5.23 ± 0.16 5.70 ± 0.22
Hemoglobin (g/L) 127.66 ± 1.69 126.96 ± 1.71
platelets (× 109/L) 229.10 ± 4.34 241.23 ± 6.63
CRP (mg/L) 21.81 ± 1.73 29.81 ± 2.61
PT (S) 16.04 ± 1.22 13.90 ± 0.74
APTT (S) 38.83 ± 1.38 35.58 ± 1.15
ALT (IU/L) 22.27 ± 0.91 21.48 ± 1.39
AST (IU/L) 26.54 ± 0.73 26.52 ± 1.20
  1. SBP systolic blood pressure, DBP diastolic blood pressure, SCLC small-cell lung carcinoma, COPD Chronic obstructive pulmonary disease, CHD coronary heart disease, TC total cholesterol, HDLC high density lipoprotein cholesterol, LDLC low density lipoprotein cholesterol, Apo apolipoprotein, WBC white blood cell, CRP C-reactive protein, PT prothrombin time, APTT activated partial thromboplastin time, ALT alanine aminotransferase, AST aspartate aminotransferase