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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Fibroblast growth factor 21 inhibits atherosclerosis in apoE−/− mice by ameliorating Fas-mediated apoptosis

Fig. 2

The effect of FGF21 in HUVECs is independent on the ERK signaling pathway. a Phosphorylated ERK1/2 levels were measured and quantified by western blotting HUVECs treated with FGF21 (500 ng/ml or 1000 ng/ml) for 36 h. b The efficiency of ERK1/2 was detected in HUVECs transfected with siRNA knock down of ERK1/2. c The caspase-3 activity was measured in HUVECs treated with ox-LDL with or without FGF21 and with siRNA knockdown of ERK1/2 (d) or by p-ERK1/2 inhibitor. *p < 0.05 vs. ox-LDL, N.S: no significance

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Lipids in Health and Disease

ISSN: 1476-511X