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Table 1 Baseline variables and non-alcoholic fatty liver disease (NAFLD) status at the end of follow-up according to the tertiles of nonHDLc/HDL ratio (n = 2717)

From: Non-HDL-cholesterol to HDL-cholesterol ratio is a better predictor of new-onset non-alcoholic fatty liver disease than non-HDL-cholesterol: a cohort study

Variable

nonHDLc/HDL ratio

P value

Tertile 1

Tertile 2

Tertile 3

(0.44–1.65; n = 906)

(1.66–2.36; n = 905)

(2.37–6.05; n = 906)

 

Age (yr)

38.83 ± 12.16

40.97 ± 12.19

42.11 ± 11.41

< 0.001

Sex, n (%)

   

< 0.001

 Female

556 (61.37)

458 (50.61)

315 (34.77)

 

 Male

350 (38.63)

447 (49.39)

591 (65.23)

 

Body mass index (kg/m2)

21.12 ± 2.36

22.25 ± 2.57

23.47 ± 2.51

< 0.001

Hypertension, n (%)

64 (7.48)

103 (12.06)

142 (16.49)

< 0.001

Systolic BP (mmHg)

109.64 ± 13.33

112.55 ± 13.99

115.80 ± 14.79

< 0.001

Diastolic BP (mmHg)

73.11 ± 8.55

75.09 ± 8.88

77.80 ± 9.59

< 0.001

Fasting plasma glucose (mmol/l)

4.77 ± 0.42

4.88 ± 0.48

4.90 ± 0.51

< 0.001

Triglycerides (mmol/l)

0.83 (0.4)

1.04 (0.59)

1.55 (1)

< 0.001

Total cholesterol (mmol/l)

4.26 ± 0.68

4.67 ± 0.67

5.01 ± 0.79

< 0.001

LDLc (mmol/l)

1.99 ± 0.46

2.49 ± 0.49

2.88 ± 0.66

< 0.001

HDLc (mmol/l)

1.85 ± 0.30

1.56 ± 0.24

1.27 ± 0.22

< 0.001

ALT (U/L)

17.54 ± 9.33

20.19 ± 10.94

23.79 ± 11.81

< 0.001

AST (U/L)

20.49 ± 6.32

20.97 ± 6.41

21.81 ± 6.82

< 0.001

Incident NAFLD, n (%)

31 (3.42)

61 (6.74)

172 (18.98)

< 0.001

  1. Data are expressed as the mean ± SD, median (interquartile range), or percentage
  2. HDLc High-density lipoprotein cholesterol.; BP Blood pressure; LDLc Low-density lipoprotein cholesterol; ALT Alanine aminotransferase; AST Aspartate aminotransferase
  3. Hypertension was defined as blood pressure ≥ 140/90 mmHg or use of anti-hypertensive treatment