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Table 3 The content of major neurotransmitters and their metabolites in the hippocampus

From: Ω-3 fatty acids-supplementary in gestation alleviates neuroinflammation and modulates neurochemistry in rats

Compound Virgin Parous
Control Supplementary Control Supplementary
DA (ng/g) 6.3 ± 0.8 5.0 ± 0.7 4.2 ± 0.4# 3.6 ± 0.5#
DOPAC (ng/g) 3.1 ± 0.5 2.0 ± 0.2 3.1 ± 0.7 3.5 ± 0.7
HVA (ng/g) 0.5 ± 0.1 0.4 ± 0.1 0.3 ± 0.0 0.4 ± 0.1
NE (ng/g) 3.8 ± 0.4 3.5 ± 0.5 2.7 ± 0.3 3.0 ± 0.3
MHPG (ng/g) 0.4 ± 0.0 0.3 ± 0.0 0.3 ± 0.0 0.3 ± 0.0
VMA(ng/g) 4.0 ± 0.3 3.5 ± 0.7 4.5 ± 0.4 3.5 ± 0.4
TRY (ug/g) 4.8 ± 0.3 4.0 ± 0.1 3.7 ± 0.1 4.6 ± 0.4
5-HT (ng/g) 129.6 ± 17.9 105.5 ± 14.0 108.1 ± 9.1 121.1 ± 12.3
5-HIAA (ng/g) 194.5 ± 30.3 166.8 ± 29.6 123.4 ± 9.5 71.8 ± 14.1##
5-HIAA/5-HT 1.8 ± 0.5 2.3 ± 0.6 0.7 ± 0.1 0.7 ± 0.2#
KYN (ng/g) 282.6 ± 24.5 242.4 ± 6.9 222.8 ± 8.8 239.3 ± 14.4
GABA (ug/g) 63.3 ± 5.0 49.5 ± 3.1 31.6 ± 1.5## 34.4 ± 1.5
GLU (ug/g) 0.1 ± 0.0 0.1 ± 0.0 0.1 ± 0.0 0.1 ± 0.0
GLN (ug/g) 48.3 ± 3.7 38.0 ± 3.7 29.2 ± 1.3## 32.5 ± 1.1
  1. Data are means ± SEM (n = 6–7). #p < 0.05, ##p < 0.01 compared to virgin group; *p < 0.05, **p < 0.01compared to control group