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Table 3 The content of major neurotransmitters and their metabolites in the hippocampus

From: Ω-3 fatty acids-supplementary in gestation alleviates neuroinflammation and modulates neurochemistry in rats

Compound

Virgin

Parous

Control

Supplementary

Control

Supplementary

DA (ng/g)

6.3 ± 0.8

5.0 ± 0.7

4.2 ± 0.4#

3.6 ± 0.5#

DOPAC (ng/g)

3.1 ± 0.5

2.0 ± 0.2

3.1 ± 0.7

3.5 ± 0.7

HVA (ng/g)

0.5 ± 0.1

0.4 ± 0.1

0.3 ± 0.0

0.4 ± 0.1

NE (ng/g)

3.8 ± 0.4

3.5 ± 0.5

2.7 ± 0.3

3.0 ± 0.3

MHPG (ng/g)

0.4 ± 0.0

0.3 ± 0.0

0.3 ± 0.0

0.3 ± 0.0

VMA(ng/g)

4.0 ± 0.3

3.5 ± 0.7

4.5 ± 0.4

3.5 ± 0.4

TRY (ug/g)

4.8 ± 0.3

4.0 ± 0.1

3.7 ± 0.1

4.6 ± 0.4

5-HT (ng/g)

129.6 ± 17.9

105.5 ± 14.0

108.1 ± 9.1

121.1 ± 12.3

5-HIAA (ng/g)

194.5 ± 30.3

166.8 ± 29.6

123.4 ± 9.5

71.8 ± 14.1##

5-HIAA/5-HT

1.8 ± 0.5

2.3 ± 0.6

0.7 ± 0.1

0.7 ± 0.2#

KYN (ng/g)

282.6 ± 24.5

242.4 ± 6.9

222.8 ± 8.8

239.3 ± 14.4

GABA (ug/g)

63.3 ± 5.0

49.5 ± 3.1

31.6 ± 1.5##

34.4 ± 1.5

GLU (ug/g)

0.1 ± 0.0

0.1 ± 0.0

0.1 ± 0.0

0.1 ± 0.0

GLN (ug/g)

48.3 ± 3.7

38.0 ± 3.7

29.2 ± 1.3##

32.5 ± 1.1

  1. Data are means ± SEM (n = 6–7). #p < 0.05, ##p < 0.01 compared to virgin group; *p < 0.05, **p < 0.01compared to control group