From: Relationship of insulin resistance estimated by triglyceride glucose index to arterial stiffness
Quartile of the TyG index | p | ||||
---|---|---|---|---|---|
I (lowest) (n = 622) | II (n = 658) | III (n = 640) | IV (highest) (n = 640) | ||
Age, years | 59 ± 8 | 60 ± 8 | 61 ± 8 | 60 ± 8 | < 0.001 |
Male, n (%) | 147 (23.6) | 179 (27.2) | 224 (35.0) | 292 (45.6) | < 0.001 |
Systolic blood pressure, mmHg | 119 ± 14 | 122 ± 15 | 124 ± 15 | 127 ± 15 | < 0.001 |
Diastolic blood pressure, mmHg | 71 ± 10 | 73 ± 9 | 75 ± 9 | 77 ± 10 | < 0.001 |
Heart rate, bpm | 65 ± 9 | 66 ± 8 | 68 ± 10 | 69 ± 10 | < 0.001 |
Anti-hypertensive drugs, n (%) | 195 (31.4) | 278 (42.2) | 295 (46.1) | 326 (50.9) | < 0.001 |
Smoking, n (%) | 114 (18.3) | 134 (20.4) | 188 (29.4) | 259 (40.5) | < 0.001 |
BMI, kg/m2 | 23.8 ± 2.9 | 24.5 ± 2.9 | 25.3 ± 2.9 | 25.8 ± 2.9 | < 0.001 |
Waist circumference, cm | 80 ± 8 | 83 ± 8 | 85 ± 8 | 87 ± 9 | < 0.001 |
Laboratory | |||||
Total cholesterol, mg/dL | 191 ± 33 | 198 ± 36 | 203 ± 37 | 205 ± 37 | < 0.001 |
Triglyceride, mg/dL | 66 ± 13 | 99 ± 13 | 133 ± 21 | 217 ± 81 | < 0.001 |
HDL cholesterol, mg/dL | 64 ± 15 | 57 ± 13 | 51 ± 13 | 45 ± 11 | < 0.001 |
LDL cholesterol, mg/dL | 114 ± 29 | 122 ± 32 | 128 ± 34 | 122 ± 35 | < 0.001 |
Fasting glucose, mg/dL | 93 ± 11 | 96 ± 11 | 101 ± 15 | 115 ± 31 | < 0.001 |
Creatinine, mg/dL | 0.76 ± 0.19 | 0.77 ± 0.18 | 0.79 ± 0.18 | 0.82 ± 0.20 | < 0.001 |
Metabolic syndrome, n (%) | 62 (10.0) | 126 (19.1) | 257 (40.2) | 507 (79.2) | < 0.001 |
Diabetes mellitus, n (%) | 45 (7.2) | 60 (9.1) | 110 (17.2) | 196 (30.6) | < 0.001 |
Anti-diabetic treatment, n (%) | 41 (6.6) | 56 (8.5) | 96 (15.0) | 154 (24.1) | < 0.001 |
TyG index | 8.7 ± 0.2 | 9.2 ± 0.1 | 9.5 ± 0.1 | 10.0 ± 0.3 | < 0.001 |