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Table 6 Association between the LIPG SNPs or their haplotypes and serum lipid traits in the Han and Maonan populations

From: LIPG SNPs, their haplotypes and gene-environment interactions on serum lipid levels

Lipid

SNP/Haplotype

Genotype/Haplotype

B

Std.error

Beta

t

P

Han

HDL-C

rs3813082 genotype

TT/TG/GG

0.050

0.020

0.120

2.506

0.013

 

rs2000813 genotype

CC/CT/TT

0.021

0.012

0.053

1.899

0.040

rs2097055 genotype

TT/CT/CC

0.052

0.021

0.065

2.520

0.012

T-C-T-A

carriers/non-carriers

0.085

0.030

0.090

2.864

0.004

T-T-C-G

carriers/non-carriers

0.055

0.023

0.069

2.355

0.019

G-T-C-G

carriers/non-carriers

−0.007

0.001

− 0.169

−5.200

0.000

ApoA1

rs2000813 genotype

CC/CT/TT

−0.010

0.002

−0.230

−4.505

0.000

Maonan

HDL-C

rs3813082 genotype

TT/TG/GG

0.097

0.025

0.124

3.968

0.000

 

rs2000813 genotype

CC/CT/TT

0.036

0.010

0.093

3.703

0.000

rs2097055 genotype

TT/CT/CC

0.072

0.023

0.098

3.106

0.002

T-C-T-A

carriers/non-carriers

−0.021

0.008

−0.073

−2.543

0.011

T-T-C-G

carriers/non-carriers

−0.013

0.006

−0.062

−2.332

0.020

G-T-C-G

carriers/non-carriers

−0.265

0.080

−0.144

−3.313

0.001

TG

rs2097055 genotype

TT/CT/CC

0.007

0.003

0.153

2.789

0.006

LDL-C

rs2097055 genotype

TT/CT/CC

−0.189

0.058

− 0.168

−3.227

0.001

 

T-T-C-G

carriers/non-carriers

−0.145

0.073

0.063

1.979

0.040

ApoA1

rs3819166 genotype

GG/AG/AA

0.002

0.001

0.158

2.838

0.005

  1. TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B, ApoA1/ApoB the ratio of apolipoprotein A1 to apolipoprotein B; B unstandardized coefficient, Beta standardized coefficient