Lipids in Health and Disease

Table 2 Nutrition sensory signal pathway alteration by prenatal dexamethasone and postnatal high-fat diet treatment

From: Obesity programmed by prenatal dexamethasone and postnatal high-fat diet leads to distinct alterations in nutrition sensory signals and circadian-clock genes in visceral adipose tissue

Nutrition sensory molecule	Prenatal Dexamethasone	Postnatal high-fat diet	h
SIRT1	→	↓	X
PGC1α	→	↓	X
mTOR	↓	↑	X
AMPK-α2	↓	↑	X
PPAR-α	↓	↑	X
PPAR-γ	↓	↑	O
GLUT4	↓	↑	O

→ no change, ↑ increase, ↓ decrease
X no interaction, O interaction

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ISSN: 1476-511X

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