Non-linear association of plasma level of high-density lipoprotein cholesterol with endobronchial biopsy bleeding in patients with lung cancer

Table 4 Threshold effect analysis of HDL-C on EBB-induced bleeding using two-piecewise linear regression

Inflection point of HDL-C (mmol/L)	EBB-induced Bleeding^a
Inflection point of HDL-C (mmol/L)	OR (95% CI)	P value
Inflection point I
< 1.4	1.03 (0.42, 2.51)	0.9554
> 1.4	0.02 (0.00, 0.41)	0.0118
Inflection point II
< 1.9	0.49 (0.25, 0.95)	0.0343
> 1.9	19.99 (0.85, 470.30)	0.0631

^aAdjust for: sex, age, smoking, location of lesion, histological type, stage of cancer, triglyceride, apolipoprotein E, PT, APTT, neutrophils and CRP. EBB, endobronchial biopsy; HDL-C, high density lipoprotein cholesterol; PT, prothrombin time; APTT, activated partial thromboplastin time; CRP, C-reactive protein

ISSN: 1476-511X