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Table 4 Threshold effect analysis of HDL-C on EBB-induced bleeding using two-piecewise linear regression

From: Non-linear association of plasma level of high-density lipoprotein cholesterol with endobronchial biopsy bleeding in patients with lung cancer

Inflection point of HDL-C (mmol/L) EBB-induced Bleedinga
OR (95% CI) P value
Inflection point I
  < 1.4 1.03 (0.42, 2.51) 0.9554
  > 1.4 0.02 (0.00, 0.41) 0.0118
Inflection point II
  < 1.9 0.49 (0.25, 0.95) 0.0343
  > 1.9 19.99 (0.85, 470.30) 0.0631
  1. aAdjust for: sex, age, smoking, location of lesion, histological type, stage of cancer, triglyceride, apolipoprotein E, PT, APTT, neutrophils and CRP. EBB, endobronchial biopsy; HDL-C, high density lipoprotein cholesterol; PT, prothrombin time; APTT, activated partial thromboplastin time; CRP, C-reactive protein