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Table 2 Risk of dyslipidemia segregated by quartiles of hepcidin, serum iron, ferritin, transferrin and sTfR

From: Iron metabolism and its association with dyslipidemia risk in children and adolescents: a cross-sectional study

 

Q1

Q2

Q3

Q4

P for trend

Serum Iron

 Male(μmol/L)

< 12.30

12.30–15.70

15.70–20.00

> 20.00

 

 Female (μmol/L)

< 12.10

12.10–15.90

15.90–19.40

> 19.40

 

 Dyslipidemia (n, %)

184 (46.7)

187 (44.5)

163 (41.4)

172 (42.9)

 

 Crude OR

1

0.92 (0.70,1.21)

0.81 (0.61,1.07)

0.86 (0.65,1.13)

0.192

 Adjusted OR1

1

1.01 (0.70,1.47)

0.89 (0.61,1.29)

0.94 (0.65,1.37)

0.589

Transferrin

 Male(μg/L)

< 2.04

2.04–2.33

2.33–2.65

> 2.65

 

 Female (μg/L)

< 2.04

2.04–2.31

2.31–2.63

> 2.63

 

 Dyslipidemia (n, %)

221 (55.3)

184 (44.9)

146 (36.2)

151 (38.2)

 

 Crude OR

1

0.66 (0.50,0.87) **

0.46 (0.35,0.61) **

0.50 (0.38,0.67) **

< 0.001

 Adjusted OR1

1

0.66 (0.45,0.95) *

0.51 (0.34,0.74) **

0.49 (0.33,0.71) **

0.015

Ferritin

 Male(g/L)

< 46.00

46.00–64.00

64.00–90.00

> 90.00

 

 Female(g/L)

< 37.00

37.00–55.00

55.00–74.00

> 74.00

 

 Dyslipidemia (n, %)

163 (43.0)

185 (44.0)

162 (42.9)

180 (46.2)

 

 Crude OR

1

1.04 (0.78,1.38)

0.99 (0.75,1.33)

1.19 (0.89,1.58)

0.312

 Adjusted OR1

1

1.31 (0.90,1.91)

1.19 (0.81,1.75)

1.15 (0.78,1.70)

0.644

sTfR

 Male(mg/L)

< 2.70

2.70–3.20

3.20–3.80

> 3.80

 

 Female(mg/L)

< 2.60

2.60–3.10

3.10–3.70

> 3.70

 

 Dyslipidemia (n, %)

206 (55.6)

203 (44.1)

149 (35.9)

144 (39.8)

 

 Crude OR

1

0.63 (0.48,0.83) **

0.45 (0.34,0.60) **

0.53 (0.39,0.71) **

< 0.001

 Adjusted OR 1

1

0.62 (0.43,0.90) *

0.54 (0.38,0.79) **

0.68 (0.46,0.99) *

0.026

  1. Abbreviation: sTfR Soluble transferrin receptor;
  2. 1Adjusted for age, gender, BMI, diet and physical activities
  3. *P < 0.05;
  4. **P < 0.01