Fig. 1
From: κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway
U50,488H ameliorated high fat-induced HUVEC apoptosis. HUVECs were exposed to vehicle or sodium palmitate (450 μmol/L) for 48 h, with or without U50,488H (70 μmol/L) and nor-BNI (10 μmol/L) treatment. a-b The apoptosis of HUVECs was assayed and quantified by Annexin V-FITC flow cytometry. c The cell viability of HUVECs was evaluated by CCK-8 assay. Data were presented as mean ± SEM. n = 6. High fat: sodium palmitate, U50: U50,488H, nor-BNI, nor-binaltorphimine. **P < 0.01 vs. Control, #P < 0.05 vs. High fat, $P < 0.05 vs. High fat +U50