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Table 4 Univariate correlation between eGFR CKD-EPI and APOE, APOAI, and APOB concentrations, and apolipoprotein ratios

From: Apolipoprotein E gene polymorphism and renal function are associated with apolipoprotein E concentration in patients with chronic kidney disease

Parameter Total APOE subgroup
E2 E3 E4
R p R p R p R p
apoE −0.11 0.32 0.68 0.002 −0.29 0.02 −0.37 0.19
apoE-HDL −0.08 0.48 0.66 0.002 −0.15 0.27 −0.31 0.28
apoE-non-HDL −0.08 0.47 0.57 0.01 −0.29 0.03 −0.25 0.38
apoE-IDL + LDL 0.09 0.39 0.78 < 0.001 −0.18 0.19 −0.18 0.54
apoE-VLDL −0.26 0.02 −0.46 0.05 −0.19 0.15 −0.16 0.58
apoAI 0.10 0.34 0.64 0.004 −0.11 0.42 0.28 0.33
apoE-HDL/apoAI −0.06 0.61 0.53 0.03 −0.11 0.43 −0.41 0.14
apoB −0.20 0.06 0.05 0.83 −0.25 0.06 −0.38 0.18
apoB-IDL + LDL −0.21 0.05 0.09 0.72 −0.28 0.04 −0.44 0.12
apoB-VLDL −0.03 0.81 −0.10 0.69 0.07 0.61 0.13 0.67
apoE/apoB in non-HDL 0.15 0.18 0.56 0.01 −0.10 0.46 0.01 0.97
apoE/apoB in IDL + LDL 0.24 0.03 0.71 < 0.001 0.02 0.89 0.07 0.82
apoE/apoB in VLDL −0.26 0.02 −0.34 0.17 −0.26 0.07 −0.17 0.56
  1. APOE - apolipoprotein E, APOAI - apolipoprotein AI, APOB - apolipoprotein B, HDL - high density lipoprotein, VLDL - very low-density lipoprotein, IDL - intermediate density lipoprotein, LDL - low density lipoprotein
  2. Subgroups: E2: ɛ2ɛ3 subjects; E3: ɛ3ɛ3 subjects; E4: ɛ3ɛ4 subjects