Table 1 GO for differentially expressed genes
From: Integrated analysis of gene expression changes associated with coronary artery disease
Category | ID | Description | GeneRatio | Adj-P | Gene ID |
|---|---|---|---|---|---|
BP | GO:0001525 | angiogenesis | 35/260 | 4.58E-13 | NR4A1/JUN/TNFAIP3/IL1B/PTGS2/EREG/BTG1/SHB/EPAS1/MMP2/GPNMB/CYR61/ENG/ITGAV/SERPINE1/HMOX1/MMP19/WNT5A/JAG1/CTGF/FN1/NRP1/VEGFA/LEF1/COL4A1/SULF1/ACKR3/CCL2/SPHK1/PLXDC1/ANGPTL4/FLT1/EMP2/ACVRL1/SLIT2 |
BP | GO:0048514 | blood vessel morphogenesis | 35/260 | 5.47E-11 | NR4A1/JUN/TNFAIP3/IL1B/PTGS2/EREG/BTG1/SHB/EPAS1/MMP2/GPNMB/CYR61/ENG/ITGAV/SERPINE1/HMOX1/MMP19/WNT5A/JAG1/CTGF/FN1/NRP1/VEGFA/LEF1/COL4A1/SULF1/ACKR3/CCL2/SPHK1/PLXDC1/ANGPTL4/FLT1/EMP2/ACVRL1/SLIT2 |
BP | GO:0030335 | positive regulation of cell migration | 31/260 | 8.84E-11 | JUN/HBEGF/PTGS2/CXCL2/ADAM9/POSTN/GPNMB/CYR61/ITGAV/SERPINE1/ICAM1/DOCK1/MET/CXCL12/CCL20/WNT5A/CXCL3/CCL7/FN1/NRP1/VEGFA/LEF1/PLPP3/ACKR3/CCL2/SPHK1/FLT1/CXCL16/KITLG/FOXP1/ITGA4 |
BP | GO:2000147 | positive regulation of cell motility | 31/260 | 1.47E-10 | JUN/HBEGF/PTGS2/CXCL2/ADAM9/POSTN/GPNMB/CYR61/ITGAV/SERPINE1/ICAM1/DOCK1/MET/CXCL12/CCL20/WNT5A/CXCL3/CCL7/FN1/NRP1/VEGFA/LEF1/PLPP3/ACKR3/CCL2/SPHK1/FLT1/CXCL16/KITLG/FOXP1/ITGA4 |
BP | GO:0040017 | positive regulation of locomotion | 32/260 | 1.47E-10 | JUN/HBEGF/PTGS2/CXCL2/ADAM9/POSTN/GPNMB/CYR61/ITGAV/SERPINE1/ICAM1/DOCK1/MET/CXCL12/CCL20/WNT5A/CXCL3/CCL7/FN1/NRP1/VEGFA/LEF1/PLPP3/ACKR3/CCL2/SPHK1/FLT1/CXCL16/KITLG/FOXP1/SLIT2/ITGA4 |
BP | GO:0051272 | positive regulation of cellular component movement | 31/260 | 1.99E-10 | JUN/HBEGF/PTGS2/CXCL2/ADAM9/POSTN/GPNMB/CYR61/ITGAV/SERPINE1/ICAM1/DOCK1/MET/CXCL12/CCL20/WNT5A/CXCL3/CCL7/FN1/NRP1/VEGFA/LEF1/PLPP3/ACKR3/CCL2/SPHK1/FLT1/CXCL16/KITLG/FOXP1/ITGA4 |
BP | GO:0030198 | extracellular matrix organization | 27/260 | 1.99E-10 | POSTN/SPP1/MMP2/HTRA1/BGN/CYR61/TIMP1/LUM/ENG/CTSL/ITGAV/SERPINE1/ICAM1/VCAM1/MMP19/MMP12/MMP10/P4HA1/CTGF/GPM6B/LAMB3/FN1/COL4A1/SULF1/JAM2/MELTF/ITGA4 |
BP | GO:0043062 | extracellular structure organization | 27/260 | 1.99E-10 | POSTN/SPP1/MMP2/HTRA1/BGN/CYR61/TIMP1/LUM/ENG/CTSL/ITGAV/SERPINE1/ICAM1/VCAM1/MMP19/MMP12/MMP10/P4HA1/CTGF/GPM6B/LAMB3/FN1/COL4A1/SULF1/JAM2/MELTF/ITGA4 |
BP | GO:0050900 | leukocyte migration | 32/260 | 2.16E-10 | TREM1/IL1B/CXCR4/CXCL2/SDC4/ITGAV/SERPINE1/ICAM1/SLC7A6/PROCR/HMOX1/CXCL12/VCAM1/CCL20/WNT5A/MERTK/CXCL3/CCL22/CCL7/OLR1/FN1/VEGFA/SDC2/FPR3/CCL2/JAM2/FLT1/CXCL16/KITLG/ATP1B3/SLIT2/ITGA4 |
BP | GO:0060326 | cell chemotaxis | 24/260 | 2.76E-10 | NR4A1/TREM1/HBEGF/IL1B/CXCR4/CXCL2/RAB13/SERPINE1/MET/CXCL12/VCAM1/CCL20/WNT5A/CXCL3/CCL22/CCL7/NRP1/VEGFA/LEF1/FPR3/CCL2/FLT1/CXCL16/SLIT2 |
BP | GO:0042326 | negative regulation of phosphorylation | 29/260 | 7.69E-09 | DUSP1/TRIB1/JUN/TNFAIP3/SOCS3/IL1B/DUSP2/CISH/DACT1/DDIT4/BGN/PPIF/ENG/WWTR1/TRIB2/GPRC5A/DUSP4/SMAD6/FBP1/INHBA/PLPP3/SPRED2/PKIB/ERRFI1/SPRED1/CNKSR3/SOCS6/SLIT2/TNIP1 |
BP | GO:0016049 | cell growth | 30/260 | 2.02E-08 | SGK1/HBEGF/CISH/BTG1/POSTN/IGFBP5/SPP1/HTRA1/CYR61/EMP1/GJA1/ITGAV/CXCL12/WNT5A/PPARG/CTGF/FBP1/FN1/NRP1/INHBA/VEGFA/LEF1/EPB41L3/SPHK1/CXCL16/RAPH1/ACVRL1/TMC8/SLIT2/DCUN1D3 |
BP | GO:0001558 | regulation of cell growth | 26/260 | 4.66E-08 | SGK1/HBEGF/CISH/BTG1/IGFBP5/SPP1/HTRA1/CYR61/GJA1/CXCL12/WNT5A/PPARG/CTGF/FBP1/FN1/NRP1/INHBA/VEGFA/LEF1/EPB41L3/SPHK1/CXCL16/ACVRL1/TMC8/SLIT2/DCUN1D3 |
BP | GO:0001933 | negative regulation of protein phosphorylation | 26/260 | 1.12E-07 | DUSP1/TRIB1/JUN/TNFAIP3/SOCS3/IL1B/DUSP2/CISH/DACT1/DDIT4/BGN/ENG/WWTR1/TRIB2/GPRC5A/DUSP4/SMAD6/PLPP3/SPRED2/PKIB/ERRFI1/SPRED1/CNKSR3/SOCS6/SLIT2/TNIP1 |
BP | GO:0045785 | positive regulation of cell adhesion | 25/260 | 2.89E-07 | IL1B/HLA-DRB5/CD83/CD80/ADAM9/CD59/TGM2/CYR61/MYO10/SDC4/ITGAV/ICAM1/DOCK1/CXCL12/VCAM1/WNT5A/NR4A3/FN1/VEGFA/PLPP3/CCL2/TESPA1/EMP2/IL6ST/ITGA4 |
BP | GO:0048660 | regulation of smooth muscle cell proliferation | 14/260 | 4.16E-07 | TRIB1/JUN/TNFAIP3/HBEGF/PTGS2/EREG/NAMPT/IGFBP5/TGM2/MMP2/HMOX1/NR4A3/PPARG/FOXP1 |
BP | GO:0048659 | smooth muscle cell proliferation | 14/260 | 5.55E-07 | TRIB1/JUN/TNFAIP3/HBEGF/PTGS2/EREG/NAMPT/IGFBP5/TGM2/MMP2/HMOX1/NR4A3/PPARG/FOXP1 |
BP | GO:0045765 | regulation of angiogenesis | 17/260 | 6.74E-06 | TNFAIP3/IL1B/PTGS2/BTG1/GPNMB/ENG/SERPINE1/HMOX1/WNT5A/VEGFA/SULF1/CCL2/SPHK1/ANGPTL4/FLT1/EMP2/ACVRL1 |
BP | GO:0033002 | muscle cell proliferation | 15/260 | 6.74E-06 | TRIB1/JUN/TNFAIP3/HBEGF/PTGS2/EREG/NAMPT/IGFBP5/TGM2/MMP2/GJA1/HMOX1/NR4A3/PPARG/FOXP1 |
BP | GO:0070098 | chemokine-mediated signaling pathway | 11/260 | 6.74E-06 | CXCR4/CXCL2/CXCL12/CCL20/CXCL3/CCL22/CCL7/CCRL2/ACKR3/CCL2/SLIT2 |
BP | GO:0030595 | leukocyte chemotaxis | 16/260 | 6.74E-06 | TREM1/IL1B/CXCR4/CXCL2/SERPINE1/CXCL12/CCL20/WNT5A/CXCL3/CCL22/CCL7/VEGFA/CCL2/FLT1/CXCL16/SLIT2 |
BP | GO:0032496 | response to lipopolysaccharide | 20/260 | 7.67E-06 | TRIB1/JUN/TNFAIP3/IL1B/PTGS2/CXCL2/CD80/GNG12/ADAM9/GJA1/SERPINE1/ICAM1/VCAM1/MRC1/CCL20/WNT5A/CXCL3/CCL2/CXCL16/FOXP1 |
BP | GO:0018108 | peptidyl-tyrosine phosphorylation | 22/260 | 8.10E-06 | SOCS3/HBEGF/OSM/EREG/CD80/TTN/EFEMP1/ICAM1/GPRC5A/MET/MERTK/TXK/NRP1/VEGFA/PLPP3/FLT1/ERRFI1/KITLG/EHD4/ABI2/ABL2/IL6ST |
BP | GO:0018212 | peptidyl-tyrosine modification | 22/260 | 8.54E-06 | SOCS3/HBEGF/OSM/EREG/CD80/TTN/EFEMP1/ICAM1/GPRC5A/MET/MERTK/TXK/NRP1/VEGFA/PLPP3/FLT1/ERRFI1/KITLG/EHD4/ABI2/ABL2/IL6ST |
BP | GO:0001667 | ameboidal-type cell migration | 20/260 | 1.27E-05 | NR4A1/JUN/HBEGF/PTGS2/ADAM9/TIMP1/SDC4/RAB13/DOCK1/MET/WNT5A/NRP1/VEGFA/LEF1/EMP2/KITLG/ACVRL1/FOXP1/SLIT2/ITGA4 |
BP | GO:0002237 | response to molecule of bacterial origin | 20/260 | 1.43E-05 | TRIB1/JUN/TNFAIP3/IL1B/PTGS2/CXCL2/CD80/GNG12/ADAM9/GJA1/SERPINE1/ICAM1/VCAM1/MRC1/CCL20/WNT5A/CXCL3/CCL2/CXCL16/FOXP1 |
BP | GO:0001706 | endoderm formation | 9/260 | 1.49E-05 | DUSP1/DUSP2/MMP2/ITGAV/DUSP4/LAMB3/FN1/INHBA/ITGA4 |
BP | GO:0022617 | extracellular matrix disassembly | 11/260 | 1.51E-05 | SPP1/MMP2/HTRA1/TIMP1/CTSL/MMP19/MMP12/MMP10/LAMB3/FN1/MELTF |
BP | GO:0070371 | ERK1 and ERK2 cascade | 18/260 | 1.51E-05 | DUSP1/JUN/GPNMB/CYR61/ITGAV/ICAM1/DUSP4/CCL20/CCL22/CCL7/CTGF/FN1/NRP1/ACKR3/CCL2/ERRFI1/CNKSR3/TNIP1 |
BP | GO:0032963 | collagen metabolic process | 12/260 | 1.51E-05 | MMP2/ENG/CTSL/MMP19/MMP12/MMP10/PPARG/CTGF/CIITA/COL4A1/CCL2/ERRFI1 |
BP | GO:0048661 | positive regulation of smooth muscle cell proliferation | 10/260 | 1.53E-05 | JUN/HBEGF/PTGS2/EREG/NAMPT/TGM2/MMP2/HMOX1/NR4A3/FOXP1 |
BP | GO:0002685 | regulation of leukocyte migration | 14/260 | 1.58E-05 | CXCL2/SERPINE1/ICAM1/HMOX1/CXCL12/CCL20/WNT5A/CXCL3/CCL7/VEGFA/CCL2/KITLG/SLIT2/ITGA4 |
BP | GO:0022604 | regulation of cell morphogenesis | 23/260 | 1.69E-05 | RHOJ/POSTN/SH3D19/SPP1/MYO10/S100A13/ICAM1/DOCK1/CXCL12/WNT5A/SKIL/CCL7/FERMT2/FN1/NRP1/VEGFA/SDC2/EPB41L3/CSNK1D/CCL2/MELTF/ARHGAP18/SLIT2 |
BP | GO:1901342 | regulation of vasculature development | 17/260 | 1.69E-05 | TNFAIP3/IL1B/PTGS2/BTG1/GPNMB/ENG/SERPINE1/HMOX1/WNT5A/VEGFA/SULF1/CCL2/SPHK1/ANGPTL4/FLT1/EMP2/ACVRL1 |
CC | GO:0005578 | proteinaceous extracellular matrix | 17/270 | 0.0098426 | POSTN/MMP2/BGN/TIMP1/LUM/EFEMP1/MGP/MMP19/MMP12/MMP10/WNT5A/CTGF/LAMB3/FN1/VEGFA/COL4A1/ANGPTL4 |
MF | GO:0005126 | cytokine receptor binding | 20/264 | 2.31E-06 | IL1B/OSM/CXCL2/ENG/CXCL12/CCL20/SMAD6/CXCL3/CCL22/CCL7/INHBA/VEGFA/CCRL2/SPRED2/CCL2/CXCL16/KITLG/SPRED1/TNFSF15/IL6ST |
MF | GO:0005125 | cytokine activity | 18/264 | 2.31E-06 | IL1B/OSM/NAMPT/CXCL2/SPP1/TIMP1/CXCL12/CCL20/WNT5A/CXCL3/CCL22/CCL7/INHBA/VEGFA/CCL2/CXCL16/KITLG/TNFSF15 |
MF | GO:0019838 | growth factor binding | 13/264 | 1.55E-05 | DUSP1/IGFBP5/HTRA1/CYR61/ENG/ITGAV/S100A13/CTGF/NRP1/COL4A1/FLT1/ACVRL1/IL6ST |
MF | GO:0001968 | fibronectin binding | 7/264 | 1.61E-05 | IGFBP5/SDC4/CTSL/ITGAV/CTGF/VEGFA/ITGA4 |
MF | GO:0042379 | chemokine receptor binding | 9/264 | 2.36E-05 | CXCL2/CXCL12/CCL20/CXCL3/CCL22/CCL7/CCRL2/CCL2/CXCL16 |
MF | GO:0008009 | chemokine activity | 8/264 | 5.25E-05 | CXCL2/CXCL12/CCL20/CXCL3/CCL22/CCL7/CCL2/CXCL16 |