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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Identification and functional analysis of missense mutations in the lecithin cholesterol acyltransferase gene in a Chilean patient with hypoalphalipoproteinemia

Fig. 2

Molecular Dynamics Simulations of wild-type and variant LCAT. a Schematic representation of human LCAT (40–425) indicating important functional regions for activity and position of reported variants. b Root-mean square deviation of alpha carbons (RMSD-Cα) for WT and variant proteins during molecular dynamics. c Root-mean square fluctuation of alpha carbons (RMSF-Cα) for WT and variant proteins during molecular dynamics. Functional regions are depicted as bars with the color corresponding to panel “a”

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Lipids in Health and Disease

ISSN: 1476-511X