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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Role of ω3 polyunsaturated fatty acids in diabetic retinopathy: a morphological and metabolically cross talk among blood retina barriers damage, autoimmunity and chronic inflammation

Fig. 2

Higher magnification of the layers 1 and 2 of normal retina as depicted in Fig. 1. It is mainly constituted by axons obliquely sectioned (a) of ganglion neurons and inner limiting layer with nuclei (N) of two Müller cells and their delicate extensions (*) containing some organelles (mitochondria –m-, RER) and neurofibrils, leaning on the inner Bruch membrane (BM). Some few small blood vessel (bv) are identified. Developed tight junctions complexes (zonulae occludens and adherens, ZO, ZA) plus normal morpho-functioning of Bruch membrane are the main morphological bases for the vitreal-retinal barrier. Dilated intercellular spaces (IC), although drawed here as usual artifacts induced by processing, may become susceptible areas for the onset of microedema and then progression to cystoid degeneration (compare with Fig. 4)

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Lipids in Health and Disease

ISSN: 1476-511X