Table 5 Mediation tests of the TG levels on the associations between the LIPC genotypes and HDL-C levels in male participants
| rs2043085 | rs1800588 | rs1532085 | ||
|---|---|---|---|---|
| Criterion 1 |
α regression coefficient Standard error P value | |||
|
0.059 0.021 0.005 |
0.063 0.021 0.004 |
0.061 0.021 0.005 | ||
| Criterion 2 |
β regression coefficient Standard error #P value | |||
|
−0.181 0.021 7.2 × 10−16 |
−0.183 0.021 2.9 × 10−16 |
− 0.181 0.021 6.5 × 10− 16 | ||
|
γ’ regression coefficient Standard error *P value | ||||
|
0.022 0.008 0.005 |
0.026 0.008 0.001 |
0.022 0.008 0.004 | ||
| Criterion 3 |
αβ + γ’ regression coefficient Standard error P value | |||
|
0.011 0.008 0.194 |
0.014 0.009 0.100 |
0.011 0.009 0.183 | ||
| Criterion 4 |
αβ regression coefficient Standard error P value (Sobel test) | |||
|
−0.011 0.004 0.008 |
−0.012 0.004 0.005 |
− 0.011 0.004 0.006 | ||