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Table 4 Effects of linoleic acid in vitro and in vivo clinical trials

From: The impact of sea buckthorn oil fatty acids on human health

Disorder

Study

Possible mechanism of action

References

Skin disorders

Guinea pigs in vivo study

Transformation of LA to 13-HODE and consequently the modulation of coetaneous hyperproliferation

Ziboh (2000) [36]

Psoriasis

Human in vivo study

Reduce the rate of relapse and rebound

Min Liu (2015)

Atherosclerosis

Rabbits in vivo study

Decrease LDL-cholesterol levels

Larmo (2013) [15]