Table 5 Effects of γ-linolenic acid in vitro and in vivo clinical trails
From: The impact of sea buckthorn oil fatty acids on human health
Disorder | Study | Possible mechanism of action | References |
|---|---|---|---|
Acne | Human in vivo study | Forming products with anti-inflammatory properties through the cyclo-oxygenase and 15-lypogenase. Also, it can improve the hyperproliferative skin condition modulating the protein kinase C. | Jung (2014) [8] |
Atopic dermatitis | Human in vivo study | It seems to play na important role as a marker of compliance but not as a therapeutic treatment | Jaw (2003) Yang (2000) [39] |
Dry eye | Human in vivo study Rat in vivo study | In combination with omega-3 fatty acids, it decreases the secretion turbidity, the meibomian gland obstruction and edema. | Pinna (2007) [40] Viau (2009) [41] |