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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Apolipoprotein-J blocks increased cell injury elicited by ox-LDL via inhibiting ROS-CaMKII pathway

Fig. 2

ApoJ attenuated the ox-LDL-stimulated ROS production. a. Nox2/gp91phox expression in NRVCs, as determined by western blotting. Ox-LDL enhanced Nox2/gp91phox expression in control adenovirus-infected cells, which was attenuated by ApoJ-overexpression (n = 4/group). b. Nox2/p47phox expression, as determined by western blotting (n = 4/group). Ox-LDL increased Nox2/p47phox expression in control adenovirus-infected NRVCs, while ApoJ overexpression prevented Nox2/p47phox expression. *P < 0.05 versus control Ad/PBS group, **P < 0.01 versus control Ad/PBS group; #P < 0.05 versus control Ad/ox-LDL group, ##P < 0.01 versus control Ad/ox-LDL group

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Lipids in Health and Disease

ISSN: 1476-511X