Age-related and gender-stratified differences in the association between high triglyceride and risk of hyperuricemia

Table 4 Odds ratio of hyperuricemia among triglyceride-glucose index in men and women^a

	Men, triglyceride-glucose index (TyG)					Women, triglyceride-glucose index (TyG)
	0 ~	1st quatile ~	2nd quatile ~	3rd quatile ~	P for trend^b	0 ~	1st quatile ~	2nd quatile ~	3rd quatile ~	P for trend^b
No. of participants	2169	3034	3410	3944		3924	3057	2701	2199
Hyperuricemia^c
Cases	103	199	333	617		67	114	198	309
Rate (%)	4.7	6.6	9.8	15.6		1.7	3.7	7.3	14.1
Model 1, OR (95% CI)	1.00	1.40 (1.10–1.79)	2.16 (1.72–2.72)	3.72 (3.00–4.62)	< 0.001	1.00	2.23 (1.64–3.33)	4.53 (3.41–6.71)	9.41 (7.19–12.33)	< 0.001
Model 2, OR (95% CI)	1.00	1.47 (1.15–1.88)	2.26 (1.80–2.85)	3.90 (3.14–4.84)	< 0.001	1.00	2.19 (1.61–2.98)	4.39 (3.29–5.86)	9.08 (6.85–12.72)	< 0.001
Model 3, OR (95% CI)	1.00	1.32 (1.03–1.72)	1.85 (1.46–2.35)	2.68 (2.11–3.41)	< 0.001	1.00	1.90 (1.39–2.61)	3.32 (2.44–4.52)	6.08 (4.43–8.34)	< 0.001

^aLogistic regression. Model 1, univariate; Model 2, adjusted with age; Model 3, adjusted with age, alanine aminotransferase (U/L), γ-glutamyl transpeptidase (U/L), serum creatinine (mmol/L), blood urea nitrogen (μmol/L), total cholesterol (mmol/L), and high density lipoprotein cholesterol (mmol/L). OR Odds ratio, CI Confidence interval
^bContrasts of marginal linear predictions after logistic regression with Stata13
^cHyperuricemia:(men > 440 μmol/L or women > 360 μmol/L