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Table 1 Previous studies regarding cut-off values of the TG/HDL-C ratio.

From: Comparison of discrimination for cardio-metabolic risk by different cut-off values of the ratio of triglycerides to HDL cholesterol

Authors, year

Age of subjects (mean or range)

Country

Cut-off values

Units (#1)

Outcome

Ref. no

McLaughlin et al. 2003

50 years (men and women with overweight)

USA

3.0 (men and women)

mg/dl

Insulin resistance

[18]

McLaughlin et al. 2005

Mean years, 42–56 (men and women)

USA

3.5 (men and women)

mg/dl

Insulin resistance

[4]

Cordero et al. 2008

42–44 years (men and women)

Spain

2.75 (men), 1.65 (women)

mg/dl

MS

[19]

Li et al. 2008

20 years or older

USA

3.0 (non-Hispanic whites and Mexican Americans); 2.0 (non-Hispanic blacks) (men and women)

mg/dl

Hyperinsulinemia

[20]

Hadaegh et al. 2010

43.3 years (men); 40.8 years (women)

Iran

4.7 (men), 3.7 (women)

mmol/L

Diabetes

[21]

Kawamoto et al. 2010

60 years (non-obese men and women); 57 (overweight men and women)

Japan

1.50 (non-obese men and women); 2.20 (overweight men and women)

mg/dl

Insulin resistance

[22]

Summer et al. 2010

55 years (African-American men and women)

USA

2.5 (men); indefinable (women)

mg/dl

Insulin resistance

[23]

Arthur et al. 2012

44.23 years (postmenopausal women)

Ghana

0.61 (women)

mmol/L

MS

[24]

Salazar et al. 2012

46 years (men); 45 years (women)

Argentine

3.5 (men); 2.5 (women)

mg/dl

Insulin resistance

[25]

Liang et al. 2013

50 years or older (postmenopausal women)

China

0.88 (women)

mmol/L

MS

[26]

Chen et al. 2014

52.30 years (men, MS-); 51.98 years (men, MS+); 49.14 years (women, MS-); 58.58 years (women, MS+)

China

1.6 (JIS criteria) and 1.2 (ATPIII criteria) (men); 1.1 (both criteria) (women)

mmol/L

MS

[27]

Gasevic et al. 2014

46.8 years (men); 47.5 years (women)

Canada

1.62 (men); 1.18 (women)

mmol/L

MS

[28]

Unger et al. 2014

45 years (MS+); 33 years (MS-)

Argentine

3.1 (men); 2.2 (women)

mg/dl

MS

[29]

Zhang et al. 2015

52.6 years (men, normal weight); 52.2 (men, high weight); 49.8 years (women, normal weight); 54.9 years (women, high weight)

China

1.51 (men); 0.84 (women)

mmol/L

Insulin resistance

[30]

Chen et al. 2016

50.61 years (men, MS+); 48.70 (men, MS-); 53.54 (women MS+); 45.57 (women, MS-)

China

1.10 (men); 0.90 (women)

mmol/L

MS

[31]

Gharipour et al., 2016

50.7 (men and women)

Iran

4.42 (men); 3.76 (women); 3.68 (men and women)

mg/dl

Ischemic heart disease and stroke (#2)

[32]

Li et al. 2016

Mean years: 49.44–53.99 (men); 48.65–56.71 (women)

China

men: 1.3 (HT), 1.3 (DL), 1.4 (DM), 1.4 (RFs); women: 0.9 (HT), 1.0 (DL), 1.0 (DM), 1.1 (RFs)

mmol/L

HT, DL, DM, RFs

[33]

Paulmichl et al. 2016

43.9 years

Austria etc.

2.05 (M value), 1.47 (M/I value)

mg/dl

Insulin resistance

[34]

Song et al. 2016

54.40 years (diabetes); 41.12 years (non-diabetes)

China

1.24 (men and women)

mmol/L

DM

[35]

Abbasian et al. 2017

30–60 years

Iran

4.03 (men); 2.86 (women)

mg/dl

MS

[36]

Kang et al. 2017

9–13 years

Korea

1.41 (men and women)

mg/dl

Insulin resistance

[37]

Deng et al. 2018

68.5 years

China

0.9 (men and women)

mmol/L

Acute ischemic stroke (#2)

[38]

  1. #1, units of triglycerides and HDL cholesterol. The TG/HDL-C value calculated using mg/dl corresponds to the product of 2.29 and the TG/HDL-C value calculated using mmol/L; #2, prospective study. ATPIII The Third Adult Treatment Panel, DL Dyslipidemia, DM, Diabetes mellitus, HT Hypertension, JIS The Joint Interim Statement, MS Metabolic syndrome, RFs two or more risk factors, Ref. no Reference number