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Fig. 11 | Lipids in Health and Disease

Fig. 11

From: 4-cholesten-3-one decreases breast cancer cell viability and alters membrane raft-localized EGFR expression by reducing lipogenesis and enhancing LXR-dependent cholesterol transporters

Fig. 11

Effect of 4-cholesten-3-one on the expression of Flotillin-2 and EGFR in membrane raft fractions. Membrane rafts were isolated from MCF-7 and MDA-MB-231 cells as described in the Materials and Methods section. The membrane raft fractions were then collected, separated by SDS-PAGE and analyzed by western blot using anti-Flotillin-2 and anti-EGFR antibodies. A representative western blot showing Flotillin-2 and EGFR expression in cancer cells treated (+) or not treated (−) with 4-cholesten-3-one

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Lipids in Health and Disease

ISSN: 1476-511X