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Table 3 Logistic OR (95% CIs) for diabetes mellitus and LDL-C stratified by quartile

From: U-shaped association between low-density lipid cholesterol and diabetes mellitus in patients with hypertension

  case/total model1 model2 model3
  OR(95%CIs) p-value OR(95%CIs) p-value OR(95%CIs) p-value
LDL-C < 3.4 mmol/L,n = 5038
Q1 337/1260 1.425(1.192,1.702) < 0.001 1.441(1.205,1.723) < 0.001 1.248(1.026,1.517) 0.027
Q2 332/1259 1.195(0.997,1.433) 0.054 1.194(0.996,1.432) 0.056 1.146(0.944,1.391) 0.168
Q3 298/1257 1.037(0.862,1.247) 0.701 1.026(0.853,1.235) 0.784 1.031(0.848,1.253) 0.761
Q4 291/1262 ref   ref   ref  
P for trend   < 0.001 < 0.001 0.015
3.4 mmol/L ≤ LDL-C < 4.1 mmol/L,n = 2847
Q1 171/712 ref   ref   ref  
Q2 142/712 0.795(0.618,1.022) 0.074 0.814(0.632,1.049) 0.112 0.806(0.618,1.051) 0.111
Q3 154/712 0.880(0.687,1.128) 0.313 0.899(0.700,1.153) 0.401 0.936(0.721,1.215) 0.619
Q4 131/711 0.708(0.548,0.915) 0.008 0.735(0.568,0.951) 0.019 0.753(0.575,0.986) 0.039
P for trend   0.023 0.047 0.105
LDLC ≥4.1 mmol/L,n = 2007
Q1 103/502 ref   ref   ref  
Q2 103/502 1.012(0.746,1.374) 0.938 1.043(0.766,1.42) 0.789 0.999(0.721,1.383) 0.994
Q3 102/501 0.990(0.729,1.346) 0.950 1.005(0.737,1.37) 0.975 0.990(0.715,1.371) 0.951
Q4 135/502 1.425(1.063,1.910) 0.018 1.489(1.108,2.003) 0.008 1.536(1.126,2.096) 0.007
P for trend   0.024 0.013 0.008
  1. model1, unadjusted;
  2. model2, adjusted for age, sex;
  3. model3, adjusted for age, sex, smoking, alcohol consumption, history of CAD, stroke, consumption of β -blockers, calcium channel blockers, ACEI/ARB, statin, BMI, SBP, DBP, TG, HDL-C and eGFR;
  4. OR, odds ratio, CIs, confidence Intervals