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Table 3 Ratios of specific sterol to cholesterol concentrations in umbilical cord vein of IUGR and CTRL neonates

From: Estimating fetal cholesterol synthesis rates by cord blood analysis in intrauterine growth restriction and normally grown fetuses

 

CTRL (n = 49)

IUGR (n = 49)

p-value

Sterol to TC ratio

μmol/mmol *10exp3

Median

95% CI

Median

95% CI

Lathosterol/TC

Ratio

2.183

(2.049–2.523)

2.081

(1.894–2.276)

0.2952

Dihydro-lanosterol/TC

Ratio

0.006

(0.005–0.008)

0.006

(0.005–0.008)

0.6267

Desmosterol/TC

Ratio

1.156

(1.080–1.259)

1.522

(1.399–1.586)

< 0.0001

Lanosterol/TC

Ratio

0.187

(0.167–0.206)

0.175

(0.145–0.206)

0.1795

24OH cholesterol/TC

Ratio

0.075

(0.065–0.084)

0.108

(0.091–0.123)

< 0.0001

27OH cholesterol/TC

Ratio

0.033

(0.030–0.035)

0.047

(0.043–0.050)

< 0.0001

β-sitosterol/TC

Ratio

0.420

(0.354–0.481)

0.478

(0.418–0.558)

0.0210

Campesterol/TC

Ratio

0.387

(0.360–0.429)

0.469

(0.437–0.569)

0.0002

5α-cholestanol/TC

Ratio

5.990

(5.426–6.489)

6.924

(6.515–7.175)

0.0004

Stigmasterol/TC

Ratio

0.075

(0.069–0.085)

0.082

(0.070–0.094)

0.1585

Brassicasterol/TC

Ratio

0.045

(0.040–0.053)

0.059

(0.055–0.066)

0.0001

  1. Significant p-values are in bold