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Table 3 Ratios of specific sterol to cholesterol concentrations in umbilical cord vein of IUGR and CTRL neonates

From: Estimating fetal cholesterol synthesis rates by cord blood analysis in intrauterine growth restriction and normally grown fetuses

  CTRL (n = 49) IUGR (n = 49) p-value
Sterol to TC ratio μmol/mmol *10exp3 Median 95% CI Median 95% CI
Lathosterol/TC Ratio 2.183 (2.049–2.523) 2.081 (1.894–2.276) 0.2952
Dihydro-lanosterol/TC Ratio 0.006 (0.005–0.008) 0.006 (0.005–0.008) 0.6267
Desmosterol/TC Ratio 1.156 (1.080–1.259) 1.522 (1.399–1.586) < 0.0001
Lanosterol/TC Ratio 0.187 (0.167–0.206) 0.175 (0.145–0.206) 0.1795
24OH cholesterol/TC Ratio 0.075 (0.065–0.084) 0.108 (0.091–0.123) < 0.0001
27OH cholesterol/TC Ratio 0.033 (0.030–0.035) 0.047 (0.043–0.050) < 0.0001
β-sitosterol/TC Ratio 0.420 (0.354–0.481) 0.478 (0.418–0.558) 0.0210
Campesterol/TC Ratio 0.387 (0.360–0.429) 0.469 (0.437–0.569) 0.0002
5α-cholestanol/TC Ratio 5.990 (5.426–6.489) 6.924 (6.515–7.175) 0.0004
Stigmasterol/TC Ratio 0.075 (0.069–0.085) 0.082 (0.070–0.094) 0.1585
Brassicasterol/TC Ratio 0.045 (0.040–0.053) 0.059 (0.055–0.066) 0.0001
  1. Significant p-values are in bold