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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Angiotensin-converting enzyme 2 regulates endoplasmic reticulum stress and mitochondrial function to preserve skeletal muscle lipid metabolism

Fig. 4

Analysis of IKKβ/NFκB/IRS-1 pathway in skeletal muscle of ACE2−/y mice. a: Relative protein levels of NFκB (p-NFκB), IKKβ (p-IKKβ), and IRS-1 (Ser307) in skeletal muscle of ACE2−/y mice. b: Proposed model of intramuscular fat metabolism amelioration by the ACE2. The up- or down-regulation of metabolic pathways is indicated by arrows. (↑ for up-regulation and ↓ for down-regulation). The data are presented as the mean ± SD of n = 3 in ACE2−/y mice. *P < 0.05 versus WT by Student’s t test

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