Table 3 Associations of the tag SNPs genotypes and serum lipid levels in the CAD patients and controls

rs2230205

CAD

GG

4.468 ± 1.133

1.330(0.975–2.125)

1.104 ± 0.270

2.822 ± 0.999

1.193 ± 0.222

0.952 ± 0.330

GA

4.653 ± 1.046

1.490(1.070–2.105)

1.066 ± 0.257

3.014 ± 0.948

1.174 ± 0.225

0.984 ± 0.285

AA

4.612 ± 1.000

1.490(1.128–2.100)

1.071 ± 0.296

2.991 ± 0.888

1.169 ± 0.215

0.978 ± 0.256

P

0.218

0.252

0.369

0.121

0.617

0.533

Control

GG

4.375 ± 0.928

1.415(0.988–2.148)

1.165 ± 0.283

2.593 ± 0.763

1.243 ± 0.226

0.893 ± 0.247

GA

4.504 ± 0.995

1.345(0.930–1.958)

1.165 ± 0.307

2.718 ± 0.837

1.242 ± 0.248

0.922 ± 0.282

AA

4.317 ± 0.860

1.340(0.940–1.930)

1.169 ± 0.358

2.566 ± 0.724

1.218 ± 0.244

0.875 ± 0.220

P

0.218

0.315

0.995

0.196

0.704

0.294

rs2287848

CAD

CC

4.578 ± 1.047

1.470(1.080–2.235)

1.071 ± 0.265

2.939 ± 0.943

1.183 ± 0.225

0.977 ± 0.296

CT

4.626 ± 1.089

1.450(1.005–1.895)

1.084 ± 0.280

2.987 ± 0.974

1.161 ± 0.216

0.969 ± 0.283

TT

4.914 ± 1.236

1.135(0.953–1.643)

1.274 ± 0.345

3.233 ± 1.028

1.246 ± 0.184

0.941 ± 0.194

P

0.617

0.165

0.100

0.617

0.391

0.913

Control

CC

4.384 ± 0.894

1.340(0.950–1.960)

1.157 ± 0.311

2.631 ± 0.730

1.219 ± 0.234

0.887 ± 0.236

CT

4.627 ± 1.129

1.430(0.990–2.180)

1.206 ± 0.320

2.736 ± 1.005

1.307 ± 0.255

0.971 ± 0.334

TT

4.120 ± 0.741

1.465(1.038–1.998)

1.035 ± 0.240

2.684 ± 0.673

1.113 ± 0.207

0.845 ± .0.141

P

0.054

0.410

0.199

0.522

0.002

0.018

rs2250656

CAD

AA

4.653 ± 1.059

1.510(1.100–2.270)

1.079 ± 0.265

3.000 ± 0.951

1.179 ± 0.206

0.983 ± 0.288

AG

4.544 ± 1.091

1.370(0.978–2.030)

1.072 ± 0.274

2.924 ± 0.962

1.178 ± 0.241

0.973 ± 0.304

GG

4.396 ± 0.867

1.350(1.030–1.750)

1.157 ± 0.297

2.684 ± 0.790

1.179 ± 0.195

0.867 ± 0.220

P

0.347

0.315

0.360

0.253

1.000

0.177

Control

AA

4.400 ± 0.894

1.370(0.990–1.470)

1.157 ± 0.300

2.648 ± 0.750

1.217 ± 0.232

0.898 ± 0.245

AG

4.557 ± 1.038

1.305(0.893–1.990)

1.191 ± 0.346

2.763 ± 0.916

1.266 ± 0.254

0.915 ± 0.268

GG

4.196 ± 1.156

1.230(0.870–1.600)

1.197 ± 0.232

2.427 ± 0.676

1.262 ± 0.256

0.801 ± 0.340

P

0.183

0.062

0.561

0.175

0.177

0.205

rs7257062

CAD

TT

4.612 ± 1.078

1.450(1.070–2.095)

1.085 ± 0.275

2.987 ± 0.990

1.187 ± 0.225

0.977 ± 0.293

TC

4.615 ± 1.053

1.470(1.050–2.110)

1.065 ± 0.268

2.947 ± 0.915

1.165 ± 0.217

0.979 ± 0.293

CC

4.378 ± 0.923

1.400(1.045–2.193)

1.086 ± 0.237

2.804 ± 0.846

1.194 ± 0.230

0.927 ± 0.266

P

0.398

0.742

0.686

0.506

0.484

0.559

Control

TT

4.483 ± 0.987

1.440(0.993–2.315)

1.152 ± 0.299

2.699 ± 0.849

1.242 ± 0.230

0.930 ± 0.283

TC

4.404 ± 0.893

1.245(0.923–1.703)

1.186 ± 0.331

2.641 ± 0.696

1.241 ± 0.251

0.8790.282

CC

4.222 ± 0.987

1.540(0.850–2.208)

1. 168 ± 0.322

2.423 ± 0.844

1.184 ± 0.278

0.860 ± 0.220

P

0.276

0.015

0.570

0.149

0.388

0.960

rs11672613

CAD

TT

4.629 ± 1.183

1.300(1.020–1.890)

1.117 ± 0.263

3.031 ± 1.104

1.195 ± 0.203

0.966 ± 0.295

TC

4.611 ± 0.978

1.560(1.130–2.300)

1.055 ± 0.263

2.941 ± 0.837

1.176 ± 0.233

0.990 ± 0.288

CC

4.500 ± 1.058

1.490(0.995–2.150)

1.067 ± 0.292

2.884 ± 0.949

1.148 ± 0.202

0.940 ± 0.284

P

0.596

0.004

0.044

0.419

0.234

0.318

Control

TT

4.460 ± 1.065

1.335(0.988–2.155)

1.158 ± 0.296

2.705 ± 0.983

1.242 ± 0.219

0.921 ± 0.280

TC

4.441 ± 0.934

1.310(0.960–1.900)

1.174 ± 0.316

2.656 ± 0.695

1.248 ± 0.253

0.907 ± 0.271

CC

4.350 ± 0.829

1.480(0.930–2.130)

1.144 ± 0.327

2.580 ± 0.746

1.194 ± 0.244

0.874 ± 0.204

P

0.692

0.412

0.784

0.545

0.217

0.446

rs2277984

CAD

AA

4.542 ± 1.006

1.350(1.015–1.990)

1.059 ± 0.250

2.976 ± 0.905

1.148 ± 0.239

0.942 ± 0.279

AG

4.599 ± 1.022

1.530(1.080–2.300)

1.073 ± 0.265

2.941 ± 0.916

1.179 ± 0.209

0.988 ± 0.287

GG

4.694 ± 1.245

1.620(1.070–2.050)

1.109 ± 0.290

2.981 ± 1.076

1.217 ± 0.212

0.985 ± 0.315

P

0.543

0.032

0.327

0.901

0.049

0.301

Control

AA

4.424 ± 1.090

1.320(0.905–1.945)

1.174 ± 0.316

2.704 ± 0.982

1.242 ± 0.240

0.907 ± 0.289

AG

4.420 ± 0.882

1.340(0.975–1.965)

1.178 ± 0.332

2.623 ± 0.694

1.245 ± 0.244

0.890 ± 0.245

GG

4.533 ± 0.939

1.450(0.940–2.170)

1.150 ± 0.256

2.708 ± 0.758

1.228 ± 0.241

0.929 ± 0.262

P

0.646

0.538

0.790

0.585

0.875

0.537

rs344555

CAD

GG

4.600 ± 0.990

1.440(1.075–2.070)

1.075 ± 0.276

2.973 ± 0.873

1.168 ± 0.213

0.974 ± 0.287

GA

4.541 ± 0.988

1.560(1.045–2.300)

1.071 ± 0.260

2.883 ± 0.896

1.179 ± 0.220

0.962 ± 0.273

AA

5.517 ± 31.687

1.490(1.190–2.390)

1.141 ± 0.274

3.261 ± 1.491

1.267 ± 0.223

1.115 ± 0.438

P

0.005

0.272

0.355

0.084

0.041

0.017

Control

GG

4.406 ± 1.029

1.305(0.938–2.013)

1.152 ± 0.296

2.681 ± 0.895

1.224 ± 0.239

0.895 ± 0.275

GA

4.440 ± 0.828

1.320(0.970–1.945)

1.203 ± 0.355

2.643 ± 0.677

1.252 ± 0.238

0.880 ± 0.213

AA

4.334 ± 0.898

1.260(0.948–1.930)

1.102 ± 0.367

2.584 ± 0.720

1.171 ± 0.264

0.908 ± 0.252

P

0.838

0.772

0.158

0.785

0.200

0.790

rs2241393

CAD

GG

4.661 ± 0.989

1.530(1.128–2.233)

1.078 ± 0.260

3.001 ± 0.944

1.200 ± 0.238

0.994 ± 0.303

GC

4.571 ± 1.126

1.440–2.060

1.076 ± 0.291

2.958 ± 1.010

1.157 ± 0.211

0.966 ± 0.290

CC

4.535 ± 0.988

1.415(0.960–2.280)

1.077 ± 0.224

2.861 ± 0.765

1.195 ± 0.216

0.959 ± 0.267

P

0.541

0.227

0.995

0.496

0.076

0.494

Control

GG

4.511 ± 1.031

1.405(0.970–2.115)

1.157 ± 0.295

2.742 ± 0.895

1.250 ± 0.232

0.928 ± 0.280

GC

4.362 ± 0.887

1.330(0.985–2.045)

1.171 ± 0.332

2.581 ± 0.720

1.236 ± 0.243

0.889 ± 0.261

CC

4.464 ± 0.955

1.360(0.850–1.910)

1.168 ± 0.292

2.670 ± 0.754

1.201 ± 0.266

0.903 ± 0.203

P

0.313

0.511

0.902

0.146

0.421

0.354