Skip to main content

Table 3 Associations of the tag SNPs genotypes and serum lipid levels in the CAD patients and controls

From: Complement C3 gene polymorphisms are associated with lipid levels, but not the risk of coronary artery disease: a case-control study

TagSNPsGroupsGenotypesTC (mmol/l)TG(mmol/l)HDL-C(mmol/l)LDL-C(mmol/l)ApoA1(g/l)ApoB (g/l)
rs2230205CADGG4.468 ± 1.1331.330(0.975–2.125)1.104 ± 0.2702.822 ± 0.9991.193 ± 0.2220.952 ± 0.330
GA4.653 ± 1.0461.490(1.070–2.105)1.066 ± 0.2573.014 ± 0.9481.174 ± 0.2250.984 ± 0.285
AA4.612 ± 1.0001.490(1.128–2.100)1.071 ± 0.2962.991 ± 0.8881.169 ± 0.2150.978 ± 0.256
P0.2180.2520.3690.1210.6170.533
ControlGG4.375 ± 0.9281.415(0.988–2.148)1.165 ± 0.2832.593 ± 0.7631.243 ± 0.2260.893 ± 0.247
GA4.504 ± 0.9951.345(0.930–1.958)1.165 ± 0.3072.718 ± 0.8371.242 ± 0.2480.922 ± 0.282
AA4.317 ± 0.8601.340(0.940–1.930)1.169 ± 0.3582.566 ± 0.7241.218 ± 0.2440.875 ± 0.220
P0.2180.3150.9950.1960.7040.294
rs2287848CADCC4.578 ± 1.0471.470(1.080–2.235)1.071 ± 0.2652.939 ± 0.9431.183 ± 0.2250.977 ± 0.296
CT4.626 ± 1.0891.450(1.005–1.895)1.084 ± 0.2802.987 ± 0.9741.161 ± 0.2160.969 ± 0.283
TT4.914 ± 1.2361.135(0.953–1.643)1.274 ± 0.3453.233 ± 1.0281.246 ± 0.1840.941 ± 0.194
P0.6170.1650.1000.6170.3910.913
ControlCC4.384 ± 0.8941.340(0.950–1.960)1.157 ± 0.3112.631 ± 0.7301.219 ± 0.2340.887 ± 0.236
CT4.627 ± 1.1291.430(0.990–2.180)1.206 ± 0.3202.736 ± 1.0051.307 ± 0.2550.971 ± 0.334
TT4.120 ± 0.7411.465(1.038–1.998)1.035 ± 0.2402.684 ± 0.6731.113 ± 0.2070.845 ± .0.141
P0.0540.4100.1990.5220.0020.018
rs2250656CADAA4.653 ± 1.0591.510(1.100–2.270)1.079 ± 0.2653.000 ± 0.9511.179 ± 0.2060.983 ± 0.288
AG4.544 ± 1.0911.370(0.978–2.030)1.072 ± 0.2742.924 ± 0.9621.178 ± 0.2410.973 ± 0.304
GG4.396 ± 0.8671.350(1.030–1.750)1.157 ± 0.2972.684 ± 0.7901.179 ± 0.1950.867 ± 0.220
P0.3470.3150.3600.2531.0000.177
ControlAA4.400 ± 0.8941.370(0.990–1.470)1.157 ± 0.3002.648 ± 0.7501.217 ± 0.2320.898 ± 0.245
AG4.557 ± 1.0381.305(0.893–1.990)1.191 ± 0.3462.763 ± 0.9161.266 ± 0.2540.915 ± 0.268
GG4.196 ± 1.1561.230(0.870–1.600)1.197 ± 0.2322.427 ± 0.6761.262 ± 0.2560.801 ± 0.340
P0.1830.0620.5610.1750.1770.205
rs7257062CADTT4.612 ± 1.0781.450(1.070–2.095)1.085 ± 0.2752.987 ± 0.9901.187 ± 0.2250.977 ± 0.293
TC4.615 ± 1.0531.470(1.050–2.110)1.065 ± 0.2682.947 ± 0.9151.165 ± 0.2170.979 ± 0.293
CC4.378 ± 0.9231.400(1.045–2.193)1.086 ± 0.2372.804 ± 0.8461.194 ± 0.2300.927 ± 0.266
P0.3980.7420.6860.5060.4840.559
ControlTT4.483 ± 0.9871.440(0.993–2.315)1.152 ± 0.2992.699 ± 0.8491.242 ± 0.2300.930 ± 0.283
TC4.404 ± 0.8931.245(0.923–1.703)1.186 ± 0.3312.641 ± 0.6961.241 ± 0.2510.8790.282
CC4.222 ± 0.9871.540(0.850–2.208)1. 168 ± 0.3222.423 ± 0.8441.184 ± 0.2780.860 ± 0.220
P0.2760.0150.5700.1490.3880.960
rs11672613CADTT4.629 ± 1.1831.300(1.020–1.890)1.117 ± 0.2633.031 ± 1.1041.195 ± 0.2030.966 ± 0.295
TC4.611 ± 0.9781.560(1.130–2.300)1.055 ± 0.2632.941 ± 0.8371.176 ± 0.2330.990 ± 0.288
CC4.500 ± 1.0581.490(0.995–2.150)1.067 ± 0.2922.884 ± 0.9491.148 ± 0.2020.940 ± 0.284
P0.5960.0040.0440.4190.2340.318
ControlTT4.460 ± 1.0651.335(0.988–2.155)1.158 ± 0.2962.705 ± 0.9831.242 ± 0.2190.921 ± 0.280
TC4.441 ± 0.9341.310(0.960–1.900)1.174 ± 0.3162.656 ± 0.6951.248 ± 0.2530.907 ± 0.271
CC4.350 ± 0.8291.480(0.930–2.130)1.144 ± 0.3272.580 ± 0.7461.194 ± 0.2440.874 ± 0.204
P0.6920.4120.7840.5450.2170.446
rs2277984CADAA4.542 ± 1.0061.350(1.015–1.990)1.059 ± 0.2502.976 ± 0.9051.148 ± 0.2390.942 ± 0.279
AG4.599 ± 1.0221.530(1.080–2.300)1.073 ± 0.2652.941 ± 0.9161.179 ± 0.2090.988 ± 0.287
GG4.694 ± 1.2451.620(1.070–2.050)1.109 ± 0.2902.981 ± 1.0761.217 ± 0.2120.985 ± 0.315
P0.5430.0320.3270.9010.0490.301
ControlAA4.424 ± 1.0901.320(0.905–1.945)1.174 ± 0.3162.704 ± 0.9821.242 ± 0.2400.907 ± 0.289
AG4.420 ± 0.8821.340(0.975–1.965)1.178 ± 0.3322.623 ± 0.6941.245 ± 0.2440.890 ± 0.245
GG4.533 ± 0.9391.450(0.940–2.170)1.150 ± 0.2562.708 ± 0.7581.228 ± 0.2410.929 ± 0.262
P0.6460.5380.7900.5850.8750.537
rs344555CADGG4.600 ± 0.9901.440(1.075–2.070)1.075 ± 0.2762.973 ± 0.8731.168 ± 0.2130.974 ± 0.287
GA4.541 ± 0.9881.560(1.045–2.300)1.071 ± 0.2602.883 ± 0.8961.179 ± 0.2200.962 ± 0.273
AA5.517 ± 31.6871.490(1.190–2.390)1.141 ± 0.2743.261 ± 1.4911.267 ± 0.2231.115 ± 0.438
P0.0050.2720.3550.0840.0410.017
ControlGG4.406 ± 1.0291.305(0.938–2.013)1.152 ± 0.2962.681 ± 0.8951.224 ± 0.2390.895 ± 0.275
GA4.440 ± 0.8281.320(0.970–1.945)1.203 ± 0.3552.643 ± 0.6771.252 ± 0.2380.880 ± 0.213
AA4.334 ± 0.8981.260(0.948–1.930)1.102 ± 0.3672.584 ± 0.7201.171 ± 0.2640.908 ± 0.252
P0.8380.7720.1580.7850.2000.790
rs2241393CADGG4.661 ± 0.9891.530(1.128–2.233)1.078 ± 0.2603.001 ± 0.9441.200 ± 0.2380.994 ± 0.303
GC4.571 ± 1.1261.440–2.0601.076 ± 0.2912.958 ± 1.0101.157 ± 0.2110.966 ± 0.290
CC4.535 ± 0.9881.415(0.960–2.280)1.077 ± 0.2242.861 ± 0.7651.195 ± 0.2160.959 ± 0.267
P0.5410.2270.9950.4960.0760.494
ControlGG4.511 ± 1.0311.405(0.970–2.115)1.157 ± 0.2952.742 ± 0.8951.250 ± 0.2320.928 ± 0.280
GC4.362 ± 0.8871.330(0.985–2.045)1.171 ± 0.3322.581 ± 0.7201.236 ± 0.2430.889 ± 0.261
CC4.464 ± 0.9551.360(0.850–1.910)1.168 ± 0.2922.670 ± 0.7541.201 ± 0.2660.903 ± 0.203
P0.3130.5110.9020.1460.4210.354
  1. CAD Coronary artery disease, TC Total cholesterol, TG Triglyceride, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol