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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: PUFAs, BDNF and lipoxin A4 inhibit chemical-induced cytotoxicity of RIN5F cells in vitro and streptozotocin-induced type 2 diabetes mellitus in vivo

Fig. 6

Measurement of BDNF (pg/ml) secretion by RIN5F cells in vitro. a) Effect of various PUFAs on the secretion of BDNF (pg/ml) by RIN5F cells in vitro that was suppressed by AL/BP. b) Effect of various PUFAs on the secretion of BDNF (pg/ml) by RIN5F cells in vitro that was suppressed by STZ (20 mM)/DB (100 ng/ml). All values expressed as mean ± SEM. *P < 0.01 vs untreated control § P < 0.001 vs toxin -treated group. AA, arachidonic acid; GLA, γ-linolenic acid; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid. c) Effect of LXA4 (10, 25, 50 and 100 ng/ml) at the end of 12, 24 and 48 h of supplementations on BDNF secretion by RIN5F cells in vitro. All values expressed as mean ± SEM. *P < 0.001 vs respective untreated control

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Lipids in Health and Disease

ISSN: 1476-511X