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Table 4 Association of the 4 APOC3 SNPs with lipid profiles in the Kuwaiti Cohort (n = 733)

From: Sequence analysis and variant identification at the APOC3 gene locus indicates association of rs5218 with BMI in a sample of Kuwaiti’s

SNP Parameters   GG   GC   CC p-value
   n   n   n   
rs5128 BMI 349 26.77 ± 0.33 131 28.03 ± 0.65 39 27.71 ± 1.05 0.08
TC 348 4.663 ± 0.511 131 4.72 ± 0.08 39 4.58 ± 0.14 0.73
TG 394 0.90 ± 0.04 131 1.00 ± 0.05 39 1.10 ± 0.15 0.05
VLDL 344 0.38 ± 0.02 129 0.41 ± 0.02 38 0.48 ± 0.07 0.06
HDL 337 1.18 ± 0.02 127 1.21 ± 0.04 36 1.19 ± 0.05 0.55
LDL 337 3.08 ± 0.04 127 3.08 ± 0.07 36 2.92 ± 0.12 0.44
rs2070668 BMI 179 27.32 ± 0.48 251 27.32 ± 0.44 89 26.41 ± 0.61 0.42
TC 179 4.67 ± 0.07 251 4.69 ± 0.062 88 4.64 ± 0.094 0.95
TG 179 0.96 ± 0.06 251 0.94 ± 0.05 89 0.86 ± 0.05 0.84
VLDL 174 0.41 ± 0.03 249 0.40 ± 0.02 88 0.36 ± 0.02 0.89
HDL 174 1.19 ± 0.02 241 1.19 ± 0.02 85 0.17 ± 0.03 0.27
LDL 174 3.04 ± 0.06 241 3.09 ± 0.05 85 3.07 ± 0.09 0.72
rs2854117 BMI 211 26.77 ± 0.42 235 27.38 ± 0.46 73 27.57 ± 0.74 0.50
TC 210 4.63 ± 0.06 235 4.67 ± 0.06 73 4.79 ± 0.10 0.55
TG 211 0.91 ± 0.05 235 0.90 ± 0.04 73 1.08 ± 0.11 0.21
VLDL 207 0.39 ± 0.02 231 0.38 ± 0.02 73 0.46 ± 0.05 0.21
HDL 202 1.17 ± 0.02 229 1.21 ± 0.02 69 0.18 ± 0.04 0.12
LDL 202 3.06 ± 0.05 229 3.05 ± 0.05 69 3.14 ± 0.09 0.66
KUAPOC3N3 BMI 514 27.12 ± 0.29 5 31.59 ± 3.34 0.14
TC 513 4.68 ± 0.04 5 4.16 ± 0.23 0.10
TG 514 0.93 ± 0.03 5 0.80 ± 0.24 0.12
VLDL 506 0.34 ± 0.01 5 0.36 ± 0.11 0.14
HDL 495 1.19 ± 0.02 5 1.02 ± 0.09 0.60
LDL 495 3.07 ± 0.04 5 2.79 ± 0.19 0.35
  1. SNP Single nucleotide polymorphism, BMI Body mass index, TC Total cholesterol, TG Triglycerides, VLDL Very low-density lipoprotein, HDL High density lipoprotein, LDL Low density lipoprotein, mmol/L millimoles per liter