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Table 3 Factors associated with better response to additional ezetimibe therapy

From: Beneficial effect of ezetimibe-atorvastatin combination therapy in patients with a mutation in ABCG5 or ABCG8 gene

Variable

OR

95% CI

p value

Age

1.09

0.87–1.31

0.29

Gender male

0.79

0.22–2.65

0.68

Hypertension

1.32

0.49–2.87

0.28

Diabetes

1.46

1.06–2.00

0.02

Smoking

0.78

0.23–2.02

0.33

Baseline LDL cholesterol (per 10 mg/dl)

1.12

0.78–1.44

0.55

ABCG5/8 mutation status

2.29

1.23–3.32

0.0034

  1. OR odds ratio, CI confidence interval, ABCG5 ATP-binding cassette sub-family G member 5, ABCG8 ATP-binding cassette sub-family G member 8