Association of Triglyceride to high-density lipoprotein cholesterol ratio and incident of diabetes mellitus: a secondary retrospective analysis based on a Chinese cohort study

Table 5 Effect size of TG/HDL-C on diabetes in prespecified and exploratory subgroups

Characteristic	No of participants	HR (95%CI)	P value	P for interacion
Age(years)				0.3871
20 to < 30	11,204	1.276 (0.745, 2.187)	0.3749
30 to < 40	41,985	1.147 (0.974, 1.352)	0.1009
40 to < 50	27,171	1.240 (1.108, 1.388)	0.0002
50 to < 60	19,569	1.089 (0.998, 1.190)	0.0561
60 to < 70	12,024	1.067 (0.970, 1.174)	0.1850
≥70	4902	1.067 (0.934, 1.218)	0.3396
Gender				0.0584
Male	62,868	1.114 (1.054, 1.177)	0.0001
Female	53,987	1.233 (1.126, 1.350)	< 0.0001
FPG				< 0.0001
< 6.1	112,483	1.296 (1.213, 1.384)	< 0.0001
≥ 6.1	4372	1.051 (0.981, 1.126)	0.1600
BMI				0.0100
< 18.5	5991	0.745 (0.180, 3.083)	0.6842
≥ 18.5, < 24	63,581	1.324 (1.206, 1.453)	< 0.0001
≥ 24, < 28	37,151	1.143 (1.065, 1.225)	0.0002
≥ 28	10,132	1.067 (0.974, 1.169)	0.1616
SBP				0.0903
< 140	104,008	1.180 (1.113, 1.250)	< 0.0001
≥ 140	12,847	1.080 (0.992, 1.176)	0.0768
DBP				0.8997
< 90	106,671	1.151 (1.090, 1.215)	< 0.0001
≥ 90	10,184	1.143 (1.034, 1.263)	0.0091
Smoking status				0.6833
Never smoker	24,684	1.154 (1.004, 1.327)	0.0441
Ever smoker	1328	0.869 (0.540, 1.398)	0.5620
Current smoker	6672	1.173 (1.007, 1.366)	0.0406
Not recorded	84,169	1.160 (1.098, 1.225)	< 0.0001
Drinking status				0.1344
Never drinker	878	1.175 (1.050, 1.314)	0.0048
Ever drinker	5535	0.908 (0.708, 1.165)	0.4475
Current drinker	26,273	1.554 (1.010, 2.391)	0.0450
Not recorded	84,169	1.159 (1.097, 1.224)	< 0.0001
Family history of diabetes				0.0251
No	114,215	1.170 (1.114, 1.228)	< 0.0001
Yes	2640	0.856 (0.649, 1.129)	0.2719

Note 1:Above model adjusted for age,gender,BMI,SBP,DBP,FPG,TC,LDL-C,SCR,smoking and drinking status,family history of diabetes
Note 2:In each case, the model is not adjusted for the stratification variable

ISSN: 1476-511X