Table 5 The effect of curcumin on plasma concentration of small dense low density lipoprotein (LDL), LDL particle number, and LDL particle size
Author, Year | Intervention | Dose per day | Treatment duration | Subjects | Method of assessment | Main outcomes | Final effects of specific diet ingredients or nutraceuticals on LDL (number, size and concentration) |
|---|---|---|---|---|---|---|---|
Panahi et al. 2014 [97] | Curcuminoids- piperine | 1000 mg/day + 10 mg piperine | 8 weeks | 117 metabolic syndrome patients | Immuno turbidimetric (sdLDL) methods with commercial kits | sdLDL levels significantly decreased in intervention group compared with baseline (− 2.73) and significant differences were observed between the two groups. | Small dense LDL↓ |
Moohebati et al. 2014 [108] | Curcuminoids- piperine | 1000 mg/day + 5 mg piperine | 4 weeks + 2 week washout phase | 30 obese dyslipidemic subjects | Immunoturbidimetric assay | No significant change in sdLDL concentrations was observed after taking curcumin supplementation compared with placebo and baseline. | Small dense LDL — |