Recovery of brain DHA-containing phosphatidylserine and ethanolamine plasmalogen after dietary DHA-enriched phosphatidylcholine and phosphatidylserine in SAMP8 mice fed with high-fat diet

Zhao, Ying-Cai; Zhou, Miao-Miao; Zhang, Ling-Yu; Cong, Pei-Xu; Xu, Jie; Xue, Chang-Hu; Yanagita, Teruyoshi; Chi, Naiqiu; Zhang, Tian-Tian; Liu, Feng-Hai; Wang, Yu-Ming

doi:10.1186/s12944-020-01253-3

Lipids in Health and Disease

Table 5 The lipid profile of PC in cerebral cortex after dietary intake of DHA enriched phospholipids

From: Recovery of brain DHA-containing phosphatidylserine and ethanolamine plasmalogen after dietary DHA-enriched phosphatidylcholine and phosphatidylserine in SAMP8 mice fed with high-fat diet

Fatty Acid (%)	LF	HF	DPC	DPS
Fatty Acid (%)	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD
13:0/22:5	0.21 ± 0.03	0.38 ± 0.08 ^**a	0.10 ± 0.05 ^b	0.14 ± 0.06 ^b
13:0/22:6	1.45 ± 0.15	1.38 ± 0.08	1.52 ± 0.29	1.32 ± 0.18
15:0/18:1	0.35 ± 0.04	0.40 ± 0.07	0.33 ± 0.09	0.32 ± 0.14
15:0/22:6	4.93 ± 0.89	5.31 ± 1.03	4.67 ± 0.59	4.98 ± 0.95
15:1/20:4	0.21 ± 0.12	0.38 ± 0.05 ^*a	0.10 ± 0.02 ^b	0.14 ± 0.06 ^b
16:0/14:0	0.26 ± 0.06	0.29 ± 0.08	0.24 ± 0.15	0.25 ± 0.03
16:0/15:0	0.27 ± 0.14	0.26 ± 0.03	0.25 ± 0.13	0.25 ± 0.06
16:0/16:0	14.72 ± 0.77	14.05 ± 1.77	14.54 ± 1.15	13.74 ± 1.88
16:0/16:1	2.98 ± 0.25	2.99 ± 0.41^a	2.19 ± 0.15 ^b	2.81 ± 0.40 ^ab
16:0/17:0	0.18 ± 0.05	0.20 ± 0.09	0.18 ± 0.03	0.17 ± 0.07
16:0/17:1	0.61 ± 0.11	0.66 ± 0.28	0.56 ± 0.29	0.55 ± 0.16
16:0/18:1	18.34 ± 2.80	18.08 ± 2.90	19.36 ± 0.58	19.27 ± 1.72
16:0/18:2	1.46 ± 0.32	1.75 ± 0.26	1.69 ± 0.32	1.90 ± 0.05
16:0/19:1	0.23 ± 0.06	0.26 ± 0.03	0.25 ± 0.07	0.23 ± 0.09
16:0/20:3	0.33 ± 0.20	0.31 ± 0.10	0.37 ± 0.21	0.33 ± 0.13
16:0/20:4	5.26 ± 0.70	5.73 ± 0.65	4.44 ± 0.44	5.22 ± 0.76
16:0/22:1	0.18 ± 0.08	0.18 ± 0.05	0.17 ± 0.04	0.17 ± 0.04
16:0/22:6	5.58 ± 0.83	5.20 ± 1.14	5.92 ± 1.56	5.23 ± 0.84
16:0/24:2	0.04 ± 0.03	0.04 ± 0.02	0.04 ± 0.03	0.04 ± 0.01
16:1/18:2	0.04 ± 0.01	0.04 ± 0.01	0.03 ± 0.02	0.04 ± 0.02
16:1/19:1	0.02 ± 0.01	0.03 ± 0.02	0.02 ± 0.02	0.02 ± 0.01
16:1/20:4	0.13 ± 0.05	0.02 ± 0.01 ^*	0.02 ± 0.01	0.03 ± 0.02
16:1/22:6	0.15 ± 0.08	0.12 ± 0.04	0.15 ± 0.07	0.14 ± 0.03
16:1/24:7	0.11 ± 0.07	0.13 ± 0.02	0.12 ± 0.03	0.13 ± 0.02
17:0/20:4	0.08 ± 0.07	0.05 ± 0.04	0.07 ± 0.03	0.05 ± 0.02
17:0/24:2	0.01 ± 0.00	0.01 ± 0.01	0.01 ± 0.00	0.01 ± 0.01
17:1/18:1	0.02 ± 0.02	0.03 ± 0.02	0.02 ± 0.01	0.02 ± 0.03
17:1/20:4	0.34 ± 0.09	0.17 ± 0.04 ^*	0.19 ± 0.04	0.13 ± 0.07
18:0/13:0	0.04 ± 0.03	0.04 ± 0.01	0.04 ± 0.01	0.03 ± 0.01
18:0/16:0	3.74 ± 0.26	3.88 ± 0.85	3.46 ± 0.77	3.70 ± 0.53
18:0/17:1	0.01 ± 0.01	0.02 ± 0.01	0.02 ± 0.01	0.02 ± 0.01
18:0/18:1	6.14 ± 1.23	6.01 ± 0.86	5.12 ± 0.62	6.10 ± 1.45
18:0/18:2	2.68 ± 0.72	1.96 ± 0.22 ^b	2.97 ± 0.70 ^ab	3.37 ± 0.13 ^a
18:0/20:4	1.10 ± 0.10	0.45 ± 0.08 ^b	3.18 ± 0.84 ^a	0.95 ± 0.20 ^b
18:0/22:1	0.03 ± 0.02	0.04 ± 0.03	0.03 ± 0.02	0.04 ± 0.02
18:0/22:6	3.53 ± 1.04	3.26 ± 0.32	3.66 ± 0.83	3.30 ± 0.88
18:0/24:1	0.02 ± 0.01	0.02 ± 0.01	0.02 ± 0.01	0.02 ± 0.01
18:0/24:2	0.02 ± 0.01	0.02 ± 0.01	0.02 ± 0.01	0.02 ± 0.01
18:1/18:2	0.17 ± 0.04	0.20 ± 0.11	0.23 ± 0.19	0.22 ± 0.17
18:1/18:3	0.90 ± 0.07	1.09 ± 0.21	0.90 ± 0.15	1.22 ± 0.19
18:1/20:4	1.60 ± 0.14	1.78 ± 0.63	1.35 ± 0.48	1.62 ± 0.31
18:1/22:6	1.28 ± 0.35	1.27 ± 0.23	1.48 ± 0.30	1.38 ± 0.29
19:0/22:1	0.01 ± 0.01	0.01 ± 0.02	0.01 ± 0.00	0.01 ± 0.00
20:0/16:0	0.06 ± 0.03	0.06 ± 0.03	0.06 ± 0.04	0.06 ± 0.04
20:0/18:2	0.23 ± 0.10	0.20 ± 0.15	0.21 ± 0.02	0.20 ± 0.05
20:0/20:4	0.28 ± 0.06	0.27 ± 0.14	0.20 ± 0.20	0.22 ± 0.03
20:0/22:4	0.02 ± 0.01	0.02 ± 0.01	0.01 ± 0.01	0.02 ± 0.01
20:1/14:0	19.13 ± 1.23	20.36 ± 2.10	19.01 ± 3.06	19.40 ± 0.71
20:1/15:0	0.02 ± 0.01	0.02 ± 0.01	0.02 ± 0.01	0.02 ± 0.01
20:1/20:4	0.07 ± 0.03	0.15 ± 0.04 ^**a	0.03 ± 0.02 ^b	0.04 ± 0.01 ^b
20:1/22:6	0.08 ± 0.01	0.07 ± 0.04	0.07 ± 0.03	0.08 ± 0.03
20:4/22:6	0.26 ± 0.05	0.26 ± 0.05	0.25 ± 0.14	0.25 ± 0.09
22:4/22:6	0.02 ± 0.02	0.03 ± 0.02	0.02 ± 0.02	0.00 ± 0.00
22:5/22:6	0.01 ± 0.00	0.01 ± 0.01^a	0.00 ± 0.00^b	0.00 ± 0.00^b
22:6/22:6	0.06 ± 0.03	0.05 ± 0.01	0.08 ± 0.04	0.06 ± 0.03

The comparison between LF and HF groups was carried out by student’s t-test *P < 0.05, **P < 0.01. Differences among two groups HF, DPC and DPS were tested by one-way ANOVA (Turkey’s test) and different letters (a, b) indicated different significance at P < 0.05

Back to article page

ISSN: 1476-511X

Contact us

General enquiries: journalsubmissions@springernature.com