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Table 1 Baseline characteristics of patients in the trials included in the meta-analysis

From: The effect of probiotics supplementation on blood pressure: a systemic review and meta-analysis

StudyCountryNo. of patientsPatients’ statusInterventionControlAge (range, y)Duration
Ivey, KL [14]Australia156Obese patientsL.acidophius La5Placebo> 556 weeks
Hariri, M [15]Iran40Type 2 diabetesL.plantarumPlacebo25–658 weeks
Hata, Y [24]Japan30HypertensionL.helveticusPlacebo40–868 weeks
Mizushima, S [25]Japan46HypertensionL.helveticusPlacebo23–594 weeks
Aihara, K [26]Japan40High-normal BPL.helveticusPlacebo52.84 weeks
 Japan40Mild hypertensionL.helveticusPlacebo51.54 weeks
Agerholm-Larsen, L [27]Denmark70ObesityEnterococcusPlacebo18–558 weeks
Hove, KD [28]Denmark41Type 2 diabetesL.helveticus card04Placebo40–7012 weeks
Naruszewicz, M [29]Poland36HealthyL.plantrarumPlacebo35–456 weeks
Seppo, L [30]Finland39HypertensionL.helveticusPlacebo30.2–61.721 weeks
Tuomilehto, J [31]Finland40HypertensionL.helveticusPlacebo51.310 weeks
Jauhiainen, T [32]Finland88HypertensionL.helveticusPlacebo5110 weeks
Chang, BJ [33]Korea101HealthyStreptococcusPlacebo20–658 weeks
Savard, P [34]Canada58HealthyYoptimalPlacebo18–554 weeks
Jones, ML [35]Canada120HyperchalesterolemicL.reuteri NCIMBPlacebo18–746 weeks
Sharafedtinov, KK [36]Russia40HypertensionL.plantarum TENSIAPlacebo30–693 weeks
Mahboobi, S [37]Iran55PrediabeticLactobacillusPlacebo25–668 weeks
Rabiei, S [38]Iran40Obese patientsL.acidophiusPlacebo25–7012 weeks
Bahmani, F [39]Iran81Type 2 diabetesL.acidophiusPlacebo8 weeks
Moller, CM [40]America105HealthyBifidobacterium brevePlacebo18–2328 days
Usinger, L [41]Denmark59HypertensionL.helveticus card04Placebo548 weeks
Szulinska, M [42]Poland71Obese postmenopausal womenlyophilisate powderPlacebo56.3812 weeks
Jauhiainen, T [43]Finland89HypertensionL.helveticusPlacebo25–5524 weeks
Barreto, FM [44]Brazil24Obese postmenopausal womenL.plantarumPlacebo6390 days