Table 1 Baseline characteristics of patients in the trials included in the meta-analysis
From: The effect of probiotics supplementation on blood pressure: a systemic review and meta-analysis
Study | Country | No. of patients | Patients’ status | Intervention | Control | Age (range, y) | Duration |
|---|---|---|---|---|---|---|---|
Ivey, KL [14] | Australia | 156 | Obese patients | L.acidophius La5 | Placebo | > 55 | 6 weeks |
Hariri, M [15] | Iran | 40 | Type 2 diabetes | L.plantarum | Placebo | 25–65 | 8 weeks |
Hata, Y [24] | Japan | 30 | Hypertension | L.helveticus | Placebo | 40–86 | 8 weeks |
Mizushima, S [25] | Japan | 46 | Hypertension | L.helveticus | Placebo | 23–59 | 4 weeks |
Aihara, K [26] | Japan | 40 | High-normal BP | L.helveticus | Placebo | 52.8 | 4 weeks |
|  | Japan | 40 | Mild hypertension | L.helveticus | Placebo | 51.5 | 4 weeks |
Agerholm-Larsen, L [27] | Denmark | 70 | Obesity | Enterococcus | Placebo | 18–55 | 8 weeks |
Hove, KD [28] | Denmark | 41 | Type 2 diabetes | L.helveticus card04 | Placebo | 40–70 | 12 weeks |
Naruszewicz, M [29] | Poland | 36 | Healthy | L.plantrarum | Placebo | 35–45 | 6 weeks |
Seppo, L [30] | Finland | 39 | Hypertension | L.helveticus | Placebo | 30.2–61.7 | 21 weeks |
Tuomilehto, J [31] | Finland | 40 | Hypertension | L.helveticus | Placebo | 51.3 | 10 weeks |
Jauhiainen, T [32] | Finland | 88 | Hypertension | L.helveticus | Placebo | 51 | 10 weeks |
Chang, BJ [33] | Korea | 101 | Healthy | Streptococcus | Placebo | 20–65 | 8 weeks |
Savard, P [34] | Canada | 58 | Healthy | Yoptimal | Placebo | 18–55 | 4 weeks |
Jones, ML [35] | Canada | 120 | Hyperchalesterolemic | L.reuteri NCIMB | Placebo | 18–74 | 6 weeks |
Sharafedtinov, KK [36] | Russia | 40 | Hypertension | L.plantarum TENSIA | Placebo | 30–69 | 3 weeks |
Mahboobi, S [37] | Iran | 55 | Prediabetic | Lactobacillus | Placebo | 25–66 | 8 weeks |
Rabiei, S [38] | Iran | 40 | Obese patients | L.acidophius | Placebo | 25–70 | 12 weeks |
Bahmani, F [39] | Iran | 81 | Type 2 diabetes | L.acidophius | Placebo | – | 8 weeks |
Moller, CM [40] | America | 105 | Healthy | Bifidobacterium breve | Placebo | 18–23 | 28 days |
Usinger, L [41] | Denmark | 59 | Hypertension | L.helveticus card04 | Placebo | 54 | 8 weeks |
Szulinska, M [42] | Poland | 71 | Obese postmenopausal women | lyophilisate powder | Placebo | 56.38 | 12 weeks |
Jauhiainen, T [43] | Finland | 89 | Hypertension | L.helveticus | Placebo | 25–55 | 24 weeks |
Barreto, FM [44] | Brazil | 24 | Obese postmenopausal women | L.plantarum | Placebo | 63 | 90 days |